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  4. Recombinant Mouse Solute carrier family 13 member 1 (Slc13a1), partial

Recombinant Mouse Solute carrier family 13 member 1 (Slc13a1), partial

  • 中文名称：
    小鼠Slc13a1重组蛋白
  • 货号：
    CSB-YP884901MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Slc13a1重组蛋白
  • 货号：
    CSB-EP884901MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Slc13a1重组蛋白
  • 货号：
    CSB-EP884901MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Slc13a1重组蛋白
  • 货号：
    CSB-BP884901MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Slc13a1重组蛋白
  • 货号：
    CSB-MP884901MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Slc13a1
  • Uniprot No.：
  • 别名：
    Slc13a1; Nas1; Nasi1; Solute carrier family 13 member 1; NaSi-1; Renal sodium/sulfate cotransporter; Na(+)/sulfate cotransporter
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney.
  • 基因功能参考文献：
    1. NaS1 is essential to maintain high maternal and fetal sulfate levels, which is important for maintaining pregnancy, placental development and normal birth weight PMID: 21403420
    2. Enhanced tumor growth in the NaS1 sulfate transporter null mouse. PMID: 19895604
    3. 1,25-(OH)(2)D(3)- and T(3)-responsive element was identified within the Nas1 promoter. PMID: 12111243
    4. This protein is a functional sulfate transporter in the kidney and intestine PMID: 12139403
    5. NaSi-1 is essential for maintaining sulfate homeostasis, and its expression is necessary for a wide range of physiological functions PMID: 14578452
    6. Wild-type mice showed a significant decrease in time to locate a hidden food reward over four trials after overnight fasting while Nas1-/- mice did not change their performance. PMID: 15794992
    7. NaS1 has a role in lipid and cholesterol metabolism PMID: 16621889
    8. Our data indicate that decreased circulating SO4 concentrations modulate 5-HT neurotransmitter and receptor levels, in a manner consistent with the behavioural phenotypes of Nas1 mice. PMID: 18007198
    9. NaS1 is essential for maintaining a normal metabolic state in the kidney and that loss of NaS1 function leads to reduced circulating steroid levels and increased urinary steroid excretion. PMID: 18790054

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  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    SLC13A/DASS transporter (TC 2.A.47) family, NADC subfamily
  • 组织特异性：
    Highly expressed in kidney and ileum, detected at lower levels in duodenum/jejunum and colon, and at very low levels in cecum, testis, adrenal and adipose tissues. Expression of isoform 2 is very low.
  • 数据库链接：

    KEGG: mmu:55961

    STRING: 10090.ENSMUSP00000031713

    UniGene: Mm.19299