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  4. Recombinant Mouse Something about silencing protein 10 (Utp3)

Recombinant Mouse Something about silencing protein 10 (Utp3)

  • 中文名称：
    小鼠Utp3重组蛋白
  • 货号：
    CSB-YP884908MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Utp3重组蛋白
  • 货号：
    CSB-EP884908MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Utp3重组蛋白
  • 货号：
    CSB-EP884908MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Utp3重组蛋白
  • 货号：
    CSB-BP884908MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Utp3重组蛋白
  • 货号：
    CSB-MP884908MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Utp3
  • Uniprot No.：
  • 别名：
    Utp3; Crl1; Crlz1; Sas10Something about silencing protein 10; Charged amino acid-rich leucine zipper 1; Crl-1; Disrupter of silencing SAS10; UTP3 homolog
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-469
  • 氨基酸序列
    MVKKSRRRGA AQWAAVRAQA GLTATDENED DLGLPPSPGD SSYYQDQVDE FHEARSRAVL AKGWNEVESG EEDGDEEEEV LPLDIDDGDD EDGESSEEEE VGEDDDGGSS VQSEAEASVD PSLSWGQRKK LYYDTDYGSK SRGRQSQQEV EEEEREEEEE AQIIQRRLAQ ALQEDDFGVA WVEAFAKPVP QVDEAETRVV KDLAKVSVKE KLKMLKKESP ELLELIEDLQ AKLTEVKDEL EPLLQLVEKG VIPTGRGSEY LKTKYNLYLN YCANISFYLI LKARRVPAHG HPVIERLVTY RNLINKLSVV DQKLSSEIRH LLTAKDGAVK KEMTPKAKLT KTKPKSVKQA AAVALTDEPD FDGAALKYYK EMEDRQELKR KKEENSAEEQ ALEEQNAKRA ITYQIAKNRG LTPRRKKIDR NPRVKHREKF RKAKIRRRGQ VREVRREEQR YSGELSGIRA GVKKSIKLK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain.
  • 基因功能参考文献：
    1. the mechanistic view that the proliferative function of Crlz-1 is caused by relaying Wnt/beta-catenin to pre-B cell receptor signaling pathways through the regulation of Runx/CBFbeta heterodimerization was verified PMID: 27226553
    2. expression of the Crlz-1 gene in mouse testis PMID: 23525569
    3. Data show that the cytoplasmic CBFbeta was shown to be mobilized into the nucleus when it was coexpressed with the nuclear Crlz1. PMID: 19735751
    4. identifies the HSS3/4 enhancer of Crlz1-IgJ locus as another target of EBG in early developmental stage of B cells PMID: 16962668
    5. H3 and H4 histones toward the chromatin of the Crlz1 gene are found to be hyperacetylated, especially on H3, in the pre-B cells, whereas those toward the chromatin of the IgJ gene are found to be hyperacetylated in the plasma cells PMID: 17015728

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    SAS10 family
  • 组织特异性：
    Detected mainly in subsets of neuronal cells of the brain. In the 17.5 dpc embryo, mainly expressed in the olfactory bulb and cerebral cortex. Postnatally, additionally expressed in the cerebellar cortex, most strongly in the hippocampus.
  • 数据库链接：

    KEGG: mmu:65961

    STRING: 10090.ENSMUSP00000087896

    UniGene: Mm.490364