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  4. Recombinant Mouse T-box transcription factor TBX22 (Tbx22)

Recombinant Mouse T-box transcription factor TBX22 (Tbx22)

  • 中文名称：
    小鼠Tbx22重组蛋白
  • 货号：
    CSB-YP817001MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Tbx22重组蛋白
  • 货号：
    CSB-EP817001MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Tbx22重组蛋白
  • 货号：
    CSB-EP817001MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Tbx22重组蛋白
  • 货号：
    CSB-BP817001MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Tbx22重组蛋白
  • 货号：
    CSB-MP817001MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Tbx22
  • Uniprot No.：
  • 别名：
    Tbx22; T-box transcription factor TBX22; T-box protein 22
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-517
  • 氨基酸序列
    MALSSRAHAF SVEALMGRPS KRKAQDPREE MQPELQEEQF VEEGEEILRS PSRDSQQPEK RLKAESSKTV FSCSDESNSQ ESLQEESVIQ VELQGSDLWK RFHDIGTEMI ITKAGRRMFP SVRIKVKGMD PVKQYYVILD VVPVDSKRYR YVYHSSQWMV AGNTDHSCIT PRFYVHPDSP CSGENWMRQI ISFDRVKLTN NEMDDKGHII LQSMHKYNPR VHVVEQDSRI DLSLIESFPT EGVKTFSFKE TEFTTVTAYQ NQQITKLKID RNPFAKGFRD PGRNRGVLDG FLETYPWMPS FSMDFKTFVT DTQSGSSGSS PVTSSGGAPS PLNSLLSPSC SPPMVYIPPS SFGMTYPDAY LHSVNIPFCY RICPTNNWRS QPFVLPTPER LPSFIIPQTL PPLMMEVPVV SSRGIINPNS GLHEDCNGQC LQASHSANQM LYGLQNPGNI FHPNAIAQEA ISYPFHPPNG CYRYTISMPP RLENVASHLS ENGTSQISFT EGSCDHSHWY PAINHYL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis.
  • 基因功能参考文献：
    1. Results demonstrate that FGF8 induces Tbx22 in the early face while BMP4 represses and thus restricts its expression. This regulation is conserved between chicken and mouse. PMID: 20845426
    2. Data show that Tbx22 is an important determinant for intramembranous bone formation in the posterior hard palate, which underpins normal palate development and function. PMID: 19648291
    3. Craniofacial expression of human and murine TBX22 correlates with the cleft palate and ankyloglossia (CPX) phenotype observed in CPX patients. PMID: 12374769
    4. primary role for Tbx22 in both palate and tongue development PMID: 12412015
    5. In mouse embryos, it is expressed in distinct areas of the head, namely the mesenchyme of the inferior nasal septum, the posterior palatal shelf before fusion, the attachment of the tongue, and mesenchymal cells surrounding the eye anlage. PMID: 12666195
    6. Mn1 and Tbx22 function in a novel molecular pathway regulating mammalian palate development. PMID: 18948418

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  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    KEGG: mmu:245572

    STRING: 10090.ENSMUSP00000128247

    UniGene: Mm.137011