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  4. Recombinant Mouse TOM1-like protein 1 (Tom1l1)

Recombinant Mouse TOM1-like protein 1 (Tom1l1)

  • 中文名称：
    小鼠Tom1l1重组蛋白
  • 货号：
    CSB-YP856386MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Tom1l1重组蛋白
  • 货号：
    CSB-EP856386MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Tom1l1重组蛋白
  • 货号：
    CSB-EP856386MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Tom1l1重组蛋白
  • 货号：
    CSB-BP856386MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Tom1l1重组蛋白
  • 货号：
    CSB-MP856386MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Tom1l1
  • Uniprot No.：
  • 别名：
    Tom1l1; Srcasm; TOM1-like protein 1; Src-activating and signaling molecule protein; Target of Myb-like protein 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-474
  • 氨基酸序列
    MAFGKSHRDP YATSVGHLIE KATFAGVLTE DWGQFLHICD IINTTQDGPK DAVKALKKRI SKNYNHKEIQ LSLSLIDMCV QNCGPSFQSL IVKKEFIKDT LVKLLNPRYT LPLETQNRIL NFIKTWSQGF PGGVDVSEVK EVYLDLLKKG VQFPPSDGEP ETRQEAGQIS PNRPTSVPTA PALSSIIAPK NPTISLVPEQ IGKLHSELDM VKMNVKVMTA ILMENTPGSE NHEDIELLRK LYKTGREMQE RIMDLLVVVE NEDVTMELIQ VNEDLNNAVL GYERFTRNQQ RLLEQKRNRT EATRTSSEPS APSCDLLDLS PIVPVPTPNE GALNSVNAQL SGLSVSSLSP VITNNLYPSL QPQRDLLASE DIEIPTLFPQ RTSQNLASSH TYDNFHSNSV LLQPVSLHTA TAAAAANQRL PPLPSSHPVL KDGDLQPPNY YEVMEFDPLA PTTEAVYEEI DGYHQKEAQS HSDC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.
  • 基因功能参考文献：
    1. Tom1L1 defines a novel mechanism for regulation of Src family of protein-tyrosine kinases mitogenic signaling induced by growth factors. PMID: 16479011
    2. Srcasm may act as a molecular "rheostat" for activated Src family tyrosine kinases PMID: 17046829
    3. Tom1L1-clathrin heavy chain (CHC) complex negatively regulates the level of SFK in caveolae needed for the induction of DNA synthesis. PMID: 17785434
  • 亚细胞定位：
    Golgi apparatus, Golgi stack. Endosome membrane. Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    TOM1 family
  • 组织特异性：
    Strongly expressed in brain and kidney, expressed at intermediate levels skin and heart, and weakly expressed in thymus. Not expressed in liver and spleen.
  • 数据库链接：

    STRING: 10090.ENSMUSP00000103500

    UniGene: Mm.167868