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  4. Recombinant Mouse TRAF3-interacting protein 1 (Traf3ip1)

Recombinant Mouse TRAF3-interacting protein 1 (Traf3ip1)

  • 中文名称：
    小鼠Traf3ip1重组蛋白
  • 货号：
    CSB-YP613532MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Traf3ip1重组蛋白
  • 货号：
    CSB-EP613532MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Traf3ip1重组蛋白
  • 货号：
    CSB-EP613532MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Traf3ip1重组蛋白
  • 货号：
    CSB-BP613532MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Traf3ip1重组蛋白
  • 货号：
    CSB-MP613532MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Traf3ip1
  • Uniprot No.：
  • 别名：
    Traf3ip1; Ift54; Mipt3; TRAF3-interacting protein 1; Intraflagellar transport protein 54 homolog; Microtubule-interacting protein associated with TRAF3; MIP-T3
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-625
  • 氨基酸序列
    MNAAVVRRTQ EALGKVIRRP PLTEKLLNKP PFRYLHDIIT EVIRITGFMK GLYTDAEMKS ENVKDKDAKI SFLQKAIDVV MMVSGEPLAA KPARIVAGHE PERTNELLQL IGKCCLSKLS SDEAVKRVLA GDKGDSRGRA QRTSKAQEPN NKSGKEEESR IHKEDKRSSE AKERSASAEH KQKEELKEDS KPREKERDKE KAKEADRDRH RDPDRDRNRD GEREKARARA KDRDRNNRDR DREAERDRER DRRSEGGKEK ERVKDRDRDR DKGRDRERRK SKNGEHTRDP DREKSRDADK PEKKSSSSGE ISRKLSDGSF KDVKAEMEAD ISVGASRSST LKPSKRRSKH SLEGDSPSDA EVEAGPAGQD KPEVMENAEV PSELPSSLRR IPRPGSARPA PPRVKRQEST ETLVVDRSGS GKTVSSVIID SQNSDNEDDE QFVVEAAPQL SEIADIDMVP SGELEDEEKH GGLVKKILET KKDYEKLQQS LKPGEKERSL IFESAWKKEK DIVSKEIEKL RVSIQTLCKS ALPLGKIMDY IQEDVDAMQN ELQLWHSENR QHAEALSQEQ SITDSAVEPL KAELSELEQQ IRDQQDKICA VKANILKNEE KIQKMVHSIN LSSRR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in epithelial morphogenesis and in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis.
  • 基因功能参考文献：
    1. Homozygous Traf3ip1 mutants are not viable and have both neural developmental defects and polydactyly, phenotypes typical of mutants with ciliary assembly defects. PMID: 21945076
    2. Data show that overexpression of IFT54/Traf3ip1 displaces IFT20 from the Golgi apparatus. IFT54s effect on IFT20 is a dominant negative phenotype caused by its overexpression. PMID: 19253336
  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    TRAF3IP1 family
  • 数据库链接：

    KEGG: mmu:74019

    STRING: 10090.ENSMUSP00000042391

    UniGene: Mm.318430