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  4. Recombinant Mouse Testis-specific gene 10 protein (Tsga10)

Recombinant Mouse Testis-specific gene 10 protein (Tsga10)

  • 中文名称：
    小鼠Tsga10重组蛋白
  • 货号：
    CSB-YP764688MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Tsga10重组蛋白
  • 货号：
    CSB-EP764688MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Tsga10重组蛋白
  • 货号：
    CSB-EP764688MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Tsga10重组蛋白
  • 货号：
    CSB-BP764688MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Tsga10重组蛋白
  • 货号：
    CSB-MP764688MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Tsga10
  • Uniprot No.：
  • 别名：
    Tsga10Testis-specific gene 10 protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-697
  • 氨基酸序列
    MMRNRSKSPR RPSPTSRAAN CDVELLKSTA RDREELKCML EKYERHLAEI QGNVKVLTSE RDKTFLLYEQ AQEEIARLRR EMMKSCKSPK STTAHAILRR VETERDVAFT DLRRMTTERD SLRERLKIAQ ETAFNEKAHL EQRIEELECT VHNLDDERME QMANMTLMKE TITTVEKEMK SLARKAMDTE SELGRQKAEN NSLRLLYENT EKDLSDTQRH LAKKKYELQL TQEKIMCLDE KIDNFTRQNI AQREEISILG ATLNDLAKEK ECLQACLDKK SENIASLGES LAMKEKTISG MKNIIAEMEQ ASRQSTEALI MCEQDISRMR RQLDETNDEL GQIARERDIL AHENDNLQEQ FAKVKQENQA LSKKLNDTHN ELSDIKQKVQ DTNLEVNKLK NILKSEESEN RQIMEQLRKA NEDAENWENK ARQTEAENNT LKLELITAEA EGNRLKEKVD ALNREVEQHL NAERSYKSQI ATLHKSLVKM EEELQKVQFE KVSALADLSS TRELCIKLDS SKELLNRQLV AKDQEIEMME NELDSARSEI ELLRSQMTNE RISMQNLEAL LVANRDKEYQ SQIALQEKES EIQLLKEHLC LAENKMAIQS RDVAQFRNVV TQLEADLDIT KRQLGTERFE RERAVQELRR QNYSSNAYNL GPMKPNTKCH SPERAHHRSP DRGLDRSLEE NLCYRDF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in spermatogenesis. When overexpressed, prevents nuclear localization of HIF1A.
  • 基因功能参考文献：
    1. This study also shows that Tsga10 expression protects sperm dysfunction in formalin plus manganese-exposed mice resulting in better preservation of spermatozoa and improvement of male fertility. PMID: 26791599
    2. Tsga10 plays a role in the sperm tail fibrous sheath. PMID: 14585816
    3. Tsga10 expression starts in 4.5-7.5 dpc mouse embryos and continues throughout embryogenesis. PMID: 16643851
    4. HIF-1alpha nuclear localization and HIF-1 transcriptional activity were significantly affected by overexpressed TSGA10 PMID: 16777103
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
  • 蛋白家族：
    CEP135/TSGA10 family
  • 组织特异性：
    Predominantly expressed in testis, in spermatozoa (at protein level). Not detected in Leydig cells. The N-terminal 27-kDa fragment is also detected in liver, while the C-terminal 55-kDa fragment is also found retina, brain and kidney (at protein level).
  • 数据库链接：

    KEGG: mmu:211484

    STRING: 10090.ENSMUSP00000048859

    UniGene: Mm.332756