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  4. Recombinant Mouse Tetratricopeptide repeat protein 39B (Ttc39b)

Recombinant Mouse Tetratricopeptide repeat protein 39B (Ttc39b)

  • 货号：
    CSB-YP807435MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP807435MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP807435MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP807435MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP807435MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ttc39b
  • Uniprot No.：
  • 别名：
    Ttc39b; T39; Tetratricopeptide repeat protein 39B; TPR repeat protein 39B
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-617
  • 氨基酸序列
    MALVGSRVEL DADEDIFEDA LETISRSPSD MATSGFHFVP CETKRTSRQL GASAMGRPEG SSAKVDLKSG LEECAEALNL FLSNKFKDAL ELLRPWAKES MYHALGYSTI VVLQAVMTFE QQDIQNGISA MKDALQTCQK YRKKCTVVES FSSLLSRGSL EQLSEEEMHA EICYAECLLQ KAALTFVQDE NMINFIKGGL KIRTSYQIYK ECLSILHVIQ KNKQEQHFFY EFEGGVKLGT GAFNLMLSLL PARIIRLLEF IGFSGNRDLG LLQLREGASG SSMRSPLCCL TILAFHTYIS LILGTGEVNV VEAESLLAPF LQQFPNGSLI LFYHARIELL KGNTEKAQET FRKCISVQEE WKQFHHLCYW ELMWIHIYQQ NWMQAYYYSD LLCKESKWSK ATYVFLKAAI LSMLPEEEVA ATKENVVSLF RQVDGLKQRI AGKSLPTEKF AVRKARRYSP PSGVPGKLVM PALEMMYVWN GFSIVGKRKD LSENLLVTVE KAEEALQNQD FTDYSVDDEC LVKLLKGCCL KNLERPLQAE LCFNHVVESE KLLKYDHYLV PFTLFELAFL YKSQGEIDKA IKVLETARNN YKDYSLESRL HFRIQAALHL WKKPSTD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Regulates high density lipoprotein (HDL) cholesterol metabolism by promoting the ubiquitination and degradation of the oxysterols receptors LXR (NR1H2 and NR1H3).
  • 基因功能参考文献：
    1. TTC39B promotes the ubiquitination and degradation of LXR; TTC39B inhibition could be an effective strategy for reducing both steatohepatitis and atherosclerosis PMID: 27383786
  • 蛋白家族：
    TTC39 family
  • 组织特异性：
    High expression in lung and spleen. Low lower expression in liver and small intestine. Weak expression in heart, brain, kidney, adipose, and adrenal gland.
  • 数据库链接：

    KEGG: mmu:69863

    STRING: 10090.ENSMUSP00000099887

    UniGene: Mm.5540