Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Mouse Zinc finger and BTB domain-containing protein 24 (Zbtb24)

Recombinant Mouse Zinc finger and BTB domain-containing protein 24 (Zbtb24)

  • 中文名称：
    小鼠Zbtb24重组蛋白
  • 货号：
    CSB-YP802246MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Zbtb24重组蛋白
  • 货号：
    CSB-EP802246MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Zbtb24重组蛋白
  • 货号：
    CSB-EP802246MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Zbtb24重组蛋白
  • 货号：
    CSB-BP802246MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Zbtb24重组蛋白
  • 货号：
    CSB-MP802246MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Zbtb24
  • Uniprot No.：
  • 别名：
    Zbtb24; Bif1; Bsg1; Znf450; Zinc finger and BTB domain-containing protein 24; Bone morphogenetic protein-induced factor 1; Brain-specific protein 1; Zinc finger protein 450
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-710
  • 氨基酸序列
    MADTTPEPCG QLMVHSDTHS DTVLASLEDQ RKKGFLCDIT LIVENVHFRA HKALLAASSE YFSMMFAEEG EIGQSIYMLE GMVADTFGIL LEFIYTGYLH ASEKTTEQIL ATAQFLKVYD LVKAYADFQD NHSAPKPPAL NCTGTPVVVI SNKKNDPLKR KRGRPRKANG LQEGRSELAA EGELQLRVNN SVQNRQNFVF KEEDSVKLSE QTPEDKESEP AGEPGSVEEV PAEKDENFDP KAGDGQESQS RCSRRRIRRS VKLKDYKLLG DEDDQSTAKR LCGRKKRSSG PEARCKDCDR VFKYSHFLAI HQRRHTGERP FKCNECGKGF AQKHSLQVHT RMHTGERPYT CTVCGKALTT KHSLLEHMSL HSGQKSFTCD QCGKYFSQKR QLKSHYRVHT GHSLPECSHC HRKFMDVSQL KKHLRTHTGE KPFTCEICGK SFTAKSSLQT HIRIHRGEKP YSCSICGKCF SDSSAKRRHC ILHTGKKPFS CPECGLQFAR LDNLKAHLKI HSKEKHTADS SSVSGSNVDE GRNILQLQPY QLSTSGEQEI QLLVTDSVHN INFMPGPSQG VSIVAAESPQ SMATDPAANI TLLTQQPEQL QGLILSAQQE QAEHIQSLSV IGGQMESSQT EPVHVITLSK ETLEHLHAHQ EQTTSSVPAA DTGARATPVP STRPGAELTQ APLAVPLDPS PGATVAGWPF GPSSYRSLKM
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in BMP2-induced transcription.
  • 基因功能参考文献：
    1. The biallelic deletion of ZBTB24 provides strong support for the hypothesis that most ICF2 patients suffer from a ZBTB24 loss of function mechanism and confirms that complete absence of ZBTB24 is compatible with human life. This is in contrast to the observed early embryonic lethality in mice lacking functional Zbtb24 PMID: 28128455
    2. Transcriptome analysis identified Cdca7 as the top down-regulated gene in Zbtb24 homozygous mutant mESCs, which can be restored by ectopic ZBTB24 expression. Finally, we show that this regulation is conserved between species and that CDCA7 levels are reduced in patients carrying ZBTB24 nonsense mutations PMID: 27466202
    3. mutation of human Zbtb24 causes ICF syndrome PMID: 21596365
    4. consistent induction of ZNF450 by BMP-2 after 4 h in three murine pluripotent cell lines suggests that ZNF450 may play a role in the BMP-2 signalling pathway PMID: 15526281
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 组织特异性：
    Widely expressed. Highest level in liver, testis and kidney.
  • 数据库链接：

    KEGG: mmu:268294

    STRING: 10090.ENSMUSP00000079592

    UniGene: Mm.258475