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  4. Recombinant Mouse Zinc finger protein 467 (Znf467)

Recombinant Mouse Zinc finger protein 467 (Znf467)

  • 中文名称：
    小鼠Znf467重组蛋白
  • 货号：
    CSB-YP026770MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Znf467重组蛋白
  • 货号：
    CSB-EP026770MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Znf467重组蛋白
  • 货号：
    CSB-EP026770MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Znf467重组蛋白
  • 货号：
    CSB-BP026770MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Znf467重组蛋白
  • 货号：
    CSB-MP026770MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Znf467
  • Uniprot No.：
  • 别名：
    Znf467; Ezi; Zfp467; MNCb-3350Zinc finger protein 467; Endothelial cell-derived zinc finger protein; EZI
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-594
  • 氨基酸序列
    MRETLEALNS LGFSVGQPEM APQSEPRDGF SNAQEKMSSR GESTLHSCSG HETPGQKEGI HTEQAEAPCM GSQASTPQKA EPAGSVPGEE WMIRKVKVED EDQEAEEEVE WPQHLSFLPS PFPTPDLGQL AVTYKLEPGT PGALGGIALS GWAPIPEKPY GCEECERRFR DQLTLRLHQR LHRGEGPCAC PDCGRSFTQR AHMLLHQRSH RGERPFPCSE CDKRFSKKAH LTRHLRTHTG ERPYPCAECG KRFSQKIHLG SHQKTHTGER PFPCTECEKR FRKKTHLIRH QRIHTGERPY QCTQCTRSFT HKQHLVRHQR VHDAASRTRS SPDIPVAPHS PTASLTPSPP GPKPFACSHC GQSFGWKKNL ATHQSLHLTE GRPFGCDECA LGTNVDPAAE PSACTPHAPD CGPGSGPAAP QRTTSSERSF FCPDCGRGFA HGQHLARHRR VHTGERPFAC AQCGRRFGSR PNLVAHSRAH SGARPFACAQ CGRRFSRKSH LGRHQAVHTG SRPHACAVCA RCFSSKTNLV RHQAIHTGSR PFSCPQCAKS FSRKTHLVRH QRIHGDAALP APASNLSAPA WSNPSEVVPP PIFF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor that promotes adipocyte differentiation and suppresses osteoblast differentiation in the bone marrow. Enhances the osteoclast-supporting ability of stromal cells. Binds with STAT3 the consensus sequence 5'-CTTCTGGGAAGA-3' of the acute phase response element (APRE). Transactivates several promoters including FOS, OSM and PPARG. Recruits a histone deacetylase complex.
  • 基因功能参考文献：
    1. these results indicate that Zfp467 regulates the differentiation of adipose-derived stem cells via a mechanism involving Sost-mediated inhibition of Wnt signaling, suggesting potential therapeutic targets for the treatment of osteoporosis. PMID: 25490389
    2. Zfp467 play an important role in adipose derived stem cells differentiation to adipocyte and osteoblast. PMID: 22252242
    3. Zfp467 is a novel co-factor that promotes adipocyte differentiation and suppresses osteoblast differentiation PMID: 21123171
    4. EZI. EZI is a novel nuclear zinc finger protein that augments STAT3 activity by keeping it in the nucleus. PMID: 12426389
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 数据库链接：

    KEGG: mmu:68910

    STRING: 10090.ENSMUSP00000110207

    UniGene: Mm.2464