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  4. Recombinant Neisseria gonorrhoeae Toxin FitB (fitB)

Recombinant Neisseria gonorrhoeae Toxin FitB (fitB)

  • 中文名称：
    Recombinant Neisseria gonorrhoeae Toxin FitB(fitB),Yeast
  • 货号：
    CSB-YP701918NGA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Neisseria gonorrhoeae Toxin FitB(fitB),Yeast
  • 货号：
    CSB-EP701918NGA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Neisseria gonorrhoeae Toxin FitB(fitB),Yeast
  • 货号：
    CSB-EP701918NGA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Neisseria gonorrhoeae Toxin FitB(fitB),Yeast
  • 货号：
    CSB-BP701918NGA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Neisseria gonorrhoeae Toxin FitB(fitB),Yeast
  • 货号：
    CSB-MP701918NGA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    fitB
  • Uniprot No.：
  • 别名：
    fitB; vapC; NGO0907Toxin FitB; Ribonuclease FitB; RNase FitB; EC 3.1.-.-; Trafficking protein B
  • 种属：
    Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-139
  • 氨基酸序列
    MILLDTNVIS EPLRPQPNER VVAWLDSLIL EDVYLSAITV AELRLGVALL LNGKKKNVLH ERLEQSILPL FAGRILPFDE PVAAIYAQIR SYAKTHGKEI AAADGYIAAT AKQHSLTVAT RDTGSFFAAD VAVFNPWHD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Toxic component of a type II toxin-antitoxin (TA) system. Plays a role in the speed with which bacteria traverse human epithelial cells; disruption of the locus increases the speed of trafficking about 2-4-fold. FitAB binds to its own promoter better than FitA alone. The expected nuclease activity was not observed for the FitAB complex, perhaps because FitA (the antitoxin) prevents metal binding and thus catalysis by FitB.
  • 基因功能参考文献：
    1. FitB was identified in a genetic screen for Neisseria gonorrhoeae determinants that affect trafficking across polarized epithelial cells. PMID: 16156663
    2. Interactions between two FitB molecules result in the formation of a tetramer of FitAB heterodimers, which binds to the 36-bp DNA fragment and provides an explanation for how FitB enhances the DNA binding affinity of FitA. PMID: 16982615
  • 蛋白家族：
    PINc/VapC protein family
  • 数据库链接：

    KEGG: ngo:NGO0907