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  4. Recombinant Neisseria meningitidis serogroup B Quinolinate synthase (nadA)

Recombinant Neisseria meningitidis serogroup B Quinolinate synthase (nadA)

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  • 中文名称：
    脑膜炎奈瑟菌血清组nadA重组蛋白
  • 货号：
    CSB-EP878213NGG
  • 规格：
    ￥2328
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP878213NGG could indicate that this peptide derived from E.coli-expressed Neisseria meningitidis serogroup B (strain MC58) nadA.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP878213NGG could indicate that this peptide derived from E.coli-expressed Neisseria meningitidis serogroup B (strain MC58) nadA.
  • 其他：

产品详情

  • 纯度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    nadA
  • Uniprot No.：
  • 别名：
    nadA; NMB0394; Quinolinate synthase A; EC 2.5.1.72
  • 种属：
    Neisseria meningitidis serogroup B (strain MC58)
  • 蛋白长度：
    Full Length
  • 来源：
    E.coli
  • 分子量：
    44.2 kDa
  • 表达区域：
    1-370aa
  • 氨基酸序列
    MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETADRLKDEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEAGTLVVAGVRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYICRETGADMLLWQGSCIVHNEFKGQELAALKAEHPEAVVLVHPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKQFIAAPTAGNGGSCKSCAFCPWMAMNSLGGIKYALTSGRNEILLDRKLGEAAKLPLQRMLDFAAGLKKKDVFNGMGPA
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
  • 基因功能参考文献：
    1. Data show that a protective conformational epitope is located in the head of Neisserial adhesin A (NadA). PMID: 25404323
    2. The prevalence and genetic diversity of pilE and nadA were investigated in the prevalent serogroups and clonal complexes of N. meningitidis isolated in China. PMID: 23290624
    3. The s demonstrate by reporter gene fusion assays that alterations of the FarR binding site within the nadA promoter are sufficient to induce transcription of nadA. PMID: 21292554
    4. Our results suggest that NadA expression is under both stochastic and tight environmental-sensing regulatory control PMID: 20041170
    5. NmFarR is a negative transcriptional regulator of the adhesin/invasin NadA. PMID: 19400792

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Quinolinate synthase A family, Type 1 subfamily
  • 数据库链接：

    KEGG: nme:NMB0394

    STRING: 122586.NMB0394