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  4. Recombinant Pan troglodytes Hemoglobin subunit beta (HBB)

Recombinant Pan troglodytes Hemoglobin subunit beta (HBB)

  • 货号：
    CSB-YP010150EQV
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP010150EQV
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP010150EQV-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP010150EQV
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP010150EQV
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    HBB; Hemoglobin subunit beta; Beta-globin; Hemoglobin beta chain
  • 种属：
    Pan troglodytes (Chimpanzee)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-147
  • 氨基酸序列
    VHLTPEEKS AVTALWGKVN VDEVGGEALG RLLVVYPWTQ RFFESFGDLS TPDAVMGNPK VKAHGKKVLG AFSDGLAHLD NLKGTFATLS ELHCDKLHVD PENFRLLGNV LVCVLAHHFG KEFTPPVQAA YQKVVAGVAN ALAHKYH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

问答及客户评论

■ 常见问题解答
Q:

Do you have them: HBB?
I am looking for the control protein for HbH (β4) and Barts (γ4) · I am studying the haemoglobin variants and I couldn't able to find these two controls for my study. The closest protein I found is HBG1.HBG2 for barts and HBB for HbH. However, I am not sure whether this is the right protein to choose.

A:
Very nice to receive your inquiry. Sorry, as the CSB-XP010150HU series proteins are discontinued, so we recommend another species, the similarity is 100%.
Recombinant Pan troglodytes Hemoglobin subunit beta(HBB)
CSB-YP010150EQV >> Yeast
CSB-EP010150EQV >> E.coli
CSB-BP010150EQV >> Baculovirus
CSB-MP010150EQV >> Mammalian cell
Expression Region: 2-147aa; Full length.
Tag information:EP: N-terminal 6xHis-SUMO-tagged; YP, BP, MP: N-terminal 6xHis-tagged
Sequence:

VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH


靶点详情

  • 功能：
    Involved in oxygen transport from the lung to the various peripheral tissues.
  • 基因功能参考文献：
    1. Pan troglodytes and Pongo pygmaeus were screened for mutations in the beta-globin gene (exons 1, 2, and 3) for suspected thalassemia. PMID: 23765979
    2. We found no evidence of the major deleterious mutations at HBB in chimpanzees that confer resistance to malaria caused by Plasmodium falciparum nor evidence of long-term balancing selection at these loci. PMID: 19631293
  • 蛋白家族：
    Globin family
  • 组织特异性：
    Red blood cells.
  • 数据库链接：

    KEGG: ptr:450978

    STRING: 9598.ENSPTRP00000005700

    UniGene: Ptr.4367