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  4. Recombinant Pig D-amino-acid oxidase (DAO)

Recombinant Pig D-amino-acid oxidase (DAO)

  • 中文名称：
    Recombinant Pig D-amino-acid oxidase(DAO),Yeast
  • 货号：
    CSB-YP006494PI
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Pig D-amino-acid oxidase(DAO),Yeast
  • 货号：
    CSB-EP006494PI
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Pig D-amino-acid oxidase(DAO),Yeast
  • 货号：
    CSB-EP006494PI-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Pig D-amino-acid oxidase(DAO),Yeast
  • 货号：
    CSB-BP006494PI
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Pig D-amino-acid oxidase(DAO),Yeast
  • 货号：
    CSB-MP006494PI
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DAO
  • Uniprot No.：
  • 别名：
    DAO; D-amino-acid oxidase; DAAO; DAMOX; DAO; EC 1.4.3.3
  • 种属：
    Sus scrofa (Pig)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-347
  • 氨基酸序列
    MRVVVIGAGV IGLSTALCIH ERYHSVLQPL DVKVYADRFT PFTTTDVAAG LWQPYTSEPS NPQEANWNQQ TFNYLLSHIG SPNAANMGLT PVSGYNLFRE AVPDPYWKDM VLGFRKLTPR ELDMFPDYRY GWFNTSLILE GRKYLQWLTE RLTERGVKFF LRKVESFEEV ARGGADVIIN CTGVWAGVLQ PDPLLQPGRG QIIKVDAPWL KNFIITHDLE RGIYNSPYII PGLQAVTLGG TFQVGNWNEI NNIQDHNTIW EGCCRLEPTL KDAKIVGEYT GFRPVRPQVR LEREQLRFGS SNTEVIHNYG HGGYGLTIHW GCALEVAKLF GKVLEERNLL TMPPSHL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
  • 基因功能参考文献：
    1. DAO suppressed the growth of Staphylococcus aureus in a manner that depended on the concentration of DAO and D-amino acid in vitro; results suggest that DAO, together with myeloperoxidase, may play an important role in antibacterial systems in mammals PMID: 22271930
    2. expression of Histamine N-Methyltransferase and Diamine Oxidase in porcine tissues PMID: 15928834
    3. The thermostable mutant DAO from porcine kidney by a single amino acid substitution, F42C, was stable at 55 degrees C, while the wild-type enzyme was stable only up to 45 degrees C. PMID: 16245349
    4. catalyzes the oxidation of D-amino acid to imino acid and its three dimensional structure is determined. PMID: 18634432
  • 亚细胞定位：
    Peroxisome.
  • 蛋白家族：
    DAMOX/DASOX family
  • 数据库链接：

    KEGG: ssc:397134

    STRING: 9823.ENSSSCP00000010609

    UniGene: Ssc.232