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  4. Recombinant Pig Dehydrogenase/reductase SDR family member 4 (DHRS4)

Recombinant Pig Dehydrogenase/reductase SDR family member 4 (DHRS4)

  • 中文名称：
    斯克罗法DHRS4重组蛋白
  • 货号：
    CSB-YP840964PI
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    斯克罗法DHRS4重组蛋白
  • 货号：
    CSB-EP840964PI
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    斯克罗法DHRS4重组蛋白
  • 货号：
    CSB-EP840964PI-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    斯克罗法DHRS4重组蛋白
  • 货号：
    CSB-BP840964PI
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    斯克罗法DHRS4重组蛋白
  • 货号：
    CSB-MP840964PI
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DHRS4
  • Uniprot No.：
  • 别名：
    DHRS4Dehydrogenase/reductase SDR family member 4; EC 1.1.1.184; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; CR; PHCR; NADPH-dependent retinol dehydrogenase/reductase; NDRD; Peroxisomal short-chain alcohol dehydrogenase; PSCD
  • 种属：
    Sus scrofa (Pig)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-279
  • 氨基酸序列
    MRAAGQLLRA CSQTWKSVRM ASTGVERRKP LENKVALVTA STDGIGLAIA RRLAQDGAHV VVSSRKQENV DRTVATLQGE GLSVTGTVCH VGKAEDRERL VAMAVNLHGG VDILVSNAAV NPFFGNIIDA TEEVWDKILH VNVKATVLMT KAVVPEMEKR GGGSVLIVSS VGAYHPFPNL GPYNVSKTAL LGLTKNLAVE LAPRNIRVNC LAPGLIKTNF SQVLWMDKAR KEYMKESLRI RRLGNPEDCA GIVSFLCSED ASYITGETVV VGGGTASRL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones.
  • 基因功能参考文献：
    1. Studied the association of postmortem pH with SNPs in the fourth member of the short-chain dehydrogenase/reductase family (DHRS4), the first member of serpin peptidase inhibitor, clade G (complement inhibitor) (SERPING1), and the apolipoprotein R precursor (APOR) genes in Berkshire pigs. Results suggest that DHRS4, SERPING1, and APOR snps may be potential genetic markers for meat quality. PMID: 28489967
    2. Sus scrofa DHRS4 gene is ortholog of human DHRS4 gene. These two genes have identical splicing phases, exon-intron structure and their coded proteins have identical catalytic amino-acid residues, Rossman fold consensus, Peroxisomal Targeting Signal consensus and the three amino-acid residues typical of vertebrate DHRS4 enzymes PMID: 23036705
    3. Peroxisomal localization of tetrameric carbonyl reductase. PMID: 18334214
  • 亚细胞定位：
    Peroxisome.
  • 蛋白家族：
    Short-chain dehydrogenases/reductases (SDR) family
  • 组织特异性：
    Detected in heart, kidney, liver and small intestine. Detected at lower levels in brain, lung, stomach and spleen.
  • 数据库链接：

    KEGG: ssc:397082

    STRING: 9823.ENSSSCP00000002200

    UniGene: Ssc.86