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  4. Recombinant Pig Pulmonary surfactant-associated protein A (SFTPA1)

Recombinant Pig Pulmonary surfactant-associated protein A (SFTPA1)

  • 中文名称：
    斯克罗法SFTPA1重组蛋白
  • 货号：
    CSB-YP021168PI
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    斯克罗法SFTPA1重组蛋白
  • 货号：
    CSB-EP021168PI
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    斯克罗法SFTPA1重组蛋白
  • 货号：
    CSB-EP021168PI-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    斯克罗法SFTPA1重组蛋白
  • 货号：
    CSB-BP021168PI
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    斯克罗法SFTPA1重组蛋白
  • 货号：
    CSB-MP021168PI
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SFTPA1
  • Uniprot No.：
  • 别名：
    SFTPA1; SFTP1; SFTPA; Pulmonary surfactant-associated protein A; PSAP; PSP-A; SP-A
  • 种属：
    Sus scrofa (Pig)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    21-249
  • 氨基酸序列
    DVKEVCLASP GIPGTPGSHG LPGRDGRDGI KGDPGPPGPM GPPGGMAGPP GQDGMIGAPG LPGERGEKGE PGERGPPGLP AHLDEELQSA LHEIRHQILQ SMGVLSFQEF MLAVGEKVFS TNGQSVAFWM SLESCVPEQV GRIAAPRSPE ENEAIASIVK KHNTYAYLGL VEGPTAGDFF YLDGTPVNYT NWYPGEPRGR GKEKCVEMYT DGQWNDRNCQ QYRLAICEF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages.
  • 基因功能参考文献：
    1. SP-A inhibited the infectivity of porcine reproductive and respiratory syndrome virus in Marc 145 cells and could reduce the total RNA and protein level. PMID: 27101074
    2. identification of a polymorphism of the porcine SFTPA1 gene coding region that is associated with acute lung injury PMID: 25442010
    3. Data suggest that transient exposure of surfactant to polymers like hyaluronan (HA) could be a promising strategy for the production of more efficient therapeutic surfactants SP-A, SP-B and SP-C preparations. PMID: 23983120
    4. PSP-A plays a significant physiological role as an antioxidant protecting the lung during the oxidative stress. PMID: 15982924
    5. Pulmonary surfactant-associated protein A (SP-A) is detected in thymus, trachea, lung, jejunum, and duodenum. PMID: 17420052

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  • 亚细胞定位：
    Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
  • 蛋白家族：
    SFTPA family
  • 数据库链接：

    STRING: 9823.ENSSSCP00000011022

    UniGene: Ssc.16255