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  4. Recombinant Pongo abelii Aldo-keto reductase family 1 member C1 homolog (AKR1C1)

Recombinant Pongo abelii Aldo-keto reductase family 1 member C1 homolog (AKR1C1)

  • 中文名称：
    Recombinant Pongo abelii Aldo-keto reductase family 1 member C1 homolog(AKR1C1),Yeast
  • 货号：
    CSB-YP716224PYX
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Pongo abelii Aldo-keto reductase family 1 member C1 homolog(AKR1C1),Yeast
  • 货号：
    CSB-EP716224PYX
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Pongo abelii Aldo-keto reductase family 1 member C1 homolog(AKR1C1),Yeast
  • 货号：
    CSB-EP716224PYX-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Pongo abelii Aldo-keto reductase family 1 member C1 homolog(AKR1C1),Yeast
  • 货号：
    CSB-BP716224PYX
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Pongo abelii Aldo-keto reductase family 1 member C1 homolog(AKR1C1),Yeast
  • 货号：
    CSB-MP716224PYX
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    AKR1C1
  • Uniprot No.：
  • 别名：
    AKR1C1Aldo-keto reductase family 1 member C1 homolog; EC 1.-.-.-; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; EC 1.1.1.149; Indanol dehydrogenase; EC 1.1.1.112
  • 种属：
    Pongo abelii (Sumatran orangutan)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-323
  • 氨基酸序列
    MDSKYQCVKL NDSHFMPVLG FGTYAPPEVP KSKALEATKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWCNSH RPELVRPALE RSLKNLQLDY VDLYLVHFPV SVKPGEEVIP KDENGKILFD TVDLCATWEA MEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNQR KLLDFCKSKD IVLVAYSALG SHREEKWVDP NSPVLLEDPV LCALAKKHKQ TPALIALRYQ LQRGVVVLAK SYNEQRIRQN MQVFDFQLTS EDMKTIDGLN RNMRYLTLDI FAGPPNYPFS DEY
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cytosolic aldo-keto reductase that catalyzes the NADH and NADPH-dependent reduction of ketosteroids to hydroxysteroids. Most probably acts as a reductase in vivo since the oxidase activity measured in vitro is inhibited by physiological concentrations of NADPH. Displays a broad positional specificity acting on positions 3, 17 and 20 of steroids and regulates the metabolism of hormones like estrogens and androgens. May also reduce conjugated steroids such as 5alpha-dihydrotestosterone sulfate. Displays affinity for bile acids.
  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Aldo/keto reductase family
  • 数据库链接：

    KEGG: pon:100171658

    STRING: 9601.ENSPPYP00000002373

    UniGene: Pab.19423