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  4. Recombinant Porphyromonas gingivalis Gingipain R1 (rgpA), partial

Recombinant Porphyromonas gingivalis Gingipain R1 (rgpA), partial

In Stock
  • 货号：
    CSB-YP338957PQP
  • 规格：
    ￥2616
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP338957PQP could indicate that this peptide derived from Yeast-expressed Porphyromonas gingivalis rgpA.
    • Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP338957PQP could indicate that this peptide derived from Yeast-expressed Porphyromonas gingivalis rgpA.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
  • Uniprot No.：
  • 别名：
    rgpA; rgp1Gingipain R1; EC 3.4.22.37; Arg-gingipain; Gingipain 1; RGP-1
  • 种属：
    Porphyromonas gingivalis
  • 蛋白长度：
    Partial
  • 来源：
    Yeast
  • 分子量：
    56.0kDa
  • 表达区域：
    228-720aa
  • 氨基酸序列
    YTPVEEKQNGRMIVIVAKKYEGDIKDFVDWKNQRGLRTEVKVAEDIASPVTANAIQQFVKQEYEKEGNDLTYVLLVGDHKDIPAKITPGIKSDQVYGQIVGNDHYNEVFIGRFSCESKEDLKTQIDRTIHYERNITTEDKWLGQALCIASAEGGPSADNGESDIQHENVIANLLTQYGYTKIIKCYDPGVTPKNIIDAFNGGISLVNYTGHGSETAWGTSHFGTTHVKQLTNSNQLPFIFDVACVNGDFLFSMPCFAEALMRAQKDGKPTGTVAIIASTINQSWASPMRGQDEMNEILCEKHPNNIKRTFGGVTMNGMFAMVEKYKKDGEKMLDTWTVFGDPSLLVRTLVPTKMQVTAPAQINLTDASVNVSCDYNGAIATISANGKMFGSAVVENGTATINLTGLTNESTLTLTVVGYNKETVIKTINTNGEPNPYQPVSNLTATTQGQKVTLKWDAPSTKTNATTNTARSVDGIRELVLLSVSDAPELLRS
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 产品描述：
        Recombinant Porphyromonas gingivalis Gingipain R1 (rgpA)是一种经重组制备的龈炎拟杆菌（Porphyromonas gingivalis）Gingipain R1蛋白。rgpA是龈炎拟杆菌中的一个重要分泌蛋白酶，对牙周疾病的发生和进展起着关键作用。
        牙周疾病是一类常见的口腔疾病，包括牙龈炎和牙周炎等。rgpA作为龈炎拟杆菌中主要的蛋白酶，可以降解牙周组织中的胶原蛋白和其他关键蛋白质，导致牙周组织的破坏和炎症反应的加剧。
        j9九游会登录入口首页生物酵母表达系统所表达的重组rgpA蛋白，表达区域为314-634aa，具有良好的稳定性和纯度，可广泛应用于实验室研究中，如分子生物学实验、蛋白质相互作用研究等。研究rgpA的功能和调控机制有助于我们更深入地了解牙周疾病的发生和发展过程，为新的牙周炎治疗策略的开发提供理论基础。此外，rgpA的研究也对开发新的抗菌药物和预防措施提供了新的靶点。
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Thiol protease. Acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable).
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Peptidase C25 family