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  4. Recombinant Probable beta-arrestin (arr-1)

Recombinant Probable beta-arrestin (arr-1)

  • 货号：
    CSB-YP344345CXY
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP344345CXY
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP344345CXY-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP344345CXY
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP344345CXY
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    arr-1
  • Uniprot No.：
  • 别名：
    arr-1; F53H8.2Beta-arrestin arr-1
  • 种属：
    Caenorhabditis elegans
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-435
  • 氨基酸序列
    MVDEDKKSGT RVFKKTSPNG KITTYLGKRD FIDRGDYVDL IDGMVLIDEE YIKDNRKVTA HLLAAFRYGR EDLDVLGLTF RKDLISETFQ VYPQTDKSIS RPLSRLQERL KRKLGANAFP FWFEVAPKSA SSVTLQPAPG DTGKPCGVDY ELKTFVAVTD GSSGEKPKKS ALSNTVRLAI RKLTYAPFES RPQPMVDVSK YFMMSSGLLH MEVSLDKEMY YHGESISVNV HIQNNSNKTV KKLKIYIIQV ADICLFTTAS YSCEVARIES NEGFPVGPGG TLSKVFAVCP LLSNNKDKRG LALDGQLKHE DTNLASSTIL DSKTSKESLG IVVQYRVKVR AVLGPLNGEL FAELPFTLTH SKPPESPERT DRGLPSIEAT NGSEPVDIDL IQLHEELEPR YDDDLIFEDF ARMRLHGNDS EDQPSPSANL PPSLL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Adapter protein required for olfactory adaptation and recovery to volatile odorants, probably by desensitization of G-protein coupled receptors (GPCR). May play a role in clathrin-mediated GPCR endocytosis. Acts as positive regulator of insulin-like daf-2 signaling pathway probably by forming a complex with mpz-1 and phosphatase daf-18 likely resulting in daf-18 inhibition. Involved in egg-laying.
  • 基因功能参考文献：
    1. We find that VANG-1 promotes Wnt signaling by facilitating Frizzled endocytosis and genetically acts in a common pathway with arr-1/beta-arrestin, whose mutation results in defective PLM branching and F-actin patterns similar to those in the Wnt, mig-1 or vang-1 mutants. On the other hand, the UNC-6/Netrin pathway intersects orthogonally with Wnt-PCP signaling to guide PLM branch growth along the dorsal-ventral axis. PMID: 28384160
    2. ARR-1 functions to regulate chemosensory signaling, enabling organisms to adapt to a variety of environmental cues, and provide an in vivo link between arrestin, receptor endocytosis, and temporal recovery from adaptation PMID: 15878875
  • 亚细胞定位：
    Perikaryon. Cell projection, dendrite.
  • 蛋白家族：
    Arrestin family
  • 组织特异性：
    Expressed in head neurons, nerve ring and ventral nerve cord (at protein level). Expressed in the nervous system including the nerve ring and the ventral and dorsal nerve cords. Highly expressed in amphid chemosensory neurons AWA, AWB, AWC, ADL and ASH, a
  • 数据库链接：

    KEGG: cel:CELE_F53H8.2

    STRING: 6239.F53H8.2

    UniGene: Cel.6957