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  4. Recombinant Pyrococcus kodakaraensis Coenzyme A disulfide reductase (TK1299)

Recombinant Pyrococcus kodakaraensis Coenzyme A disulfide reductase (TK1299)

  • 货号：
    CSB-YP683337FHY
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP683337FHY
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP683337FHY-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP683337FHY
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP683337FHY
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TK1299
  • Uniprot No.：
  • 别名：
    TK1299Coenzyme A disulfide reductase; CoA-disulfide reductase; CoADR; EC 1.8.1.14
  • 种属：
    Pyrococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Thermococcus kodakaraensis (strain KOD1))
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-442
  • 氨基酸序列
    MERKTVVVIG GGAAGMSTAS RVKRLKPEWD VKVFEATEWV SHAPCGIPYV VEGISPKEKL MHYPPEVFIK KRGIDLHLKA EVIEVEQGRV RVREEDGEKT YEWDYLVFAN GASPQVPAIE GIDLPGVFTA DLPPDAVAIT EYLEKNPVEN VVVIGTGYIA IEMAEAFVER GKNVTLIGRS ERVLRKTFDK EITDIVEEKL RNHLNLRLEE VTLRIEGKER VERVVTDAGE YPADLVIVAT GIKPNTELAR GLGVRIGETG AIWTNDRMQT SVENVYAAGD VAETKHLITG RRVWMPLAPA GNKMGYVAGS NIAGKEIHFP GVLGTSITKF LDLEIGKTGL TEAEAMKEGY DVRTAFIKAG TRPHYYPGSK TIWLKGVVDN ETNRLLGVQA VGGDILPRID TAAAMITAGF TTKDVFFTDL AYAPPFAPVW DPLIVLARVL KF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the CoA-dependent reduction of elemental sulfur (S(0)) to produce hydrogen sulfide. Can use both NADPH and NADH, but shows a preference for NADPH. CoA-SH may act to solubilize S(0) by forming CoA persulfides, followed by the reduction of an enzyme-S-S-CoA intermediate produced after both enzymatic and nonenzymatic evolution of H(2)S from the CoA persulfide. Also catalyzes the oxidation of NADPH as well as NADH and predominantly converts O(2) to H(2)O, with a preference for NADPH.
  • 基因功能参考文献：
    1. TK1299 is characterized as the most thermostable and unique NAD(P)H oxidase displaying higher enzyme activity with NADPH. PMID: 23453203
  • 蛋白家族：
    Class-III pyridine nucleotide-disulfide oxidoreductase family
  • 数据库链接：

    KEGG: tko:TK1299

    STRING: 69014.TK1299