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  4. Recombinant Rat Calretinin (Calb2)

Recombinant Rat Calretinin (Calb2)

  • 中文名称：
    Recombinant Rat Calretinin(Calb2),Yeast
  • 货号：
    CSB-YP004433RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Rat Calretinin(Calb2),Yeast
  • 货号：
    CSB-EP004433RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Rat Calretinin(Calb2),Yeast
  • 货号：
    CSB-EP004433RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Rat Calretinin(Calb2),Yeast
  • 货号：
    CSB-BP004433RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Rat Calretinin(Calb2),Yeast
  • 货号：
    CSB-MP004433RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Calb2Calretinin; CR
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-271
  • 氨基酸序列
    MAGPQQQPPY LHLAELTASQ FLEIWKHFDA DGNGYIEGKE LENFFQELEK ARKGSGMMSK SDNFGEKMKE FMQKYDKNSD GKIEMAELAQ ILPTEENFLL CFRQHVGSSA EFMEAWRKYD TDRSGYIEAN ELKGFLSDLL KKANRPYDEP KLQEYTQTIL RMFDLNGDGK LGLSEMSRLL PVQENFLLKF QGMKLTSEEF NAIFTFYDKD GSGYIDENEL DALLKDLYEK NKKEMNIQQL TTYRKSVMSL AEAGKLYRKD LEIVLCSEPP M
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Calretinin is a calcium-binding protein which is abundant in auditory neurons.
  • 基因功能参考文献：
    1. Quantitative analysis of the transient changes in calretinin expression by hybridochemistry within neuronal cell populations in the hippocampus of a beta amyloid-treated rat model of Alzheimer's disease and their correlation with endocannabinoid increase PMID: 25813826
    2. A role for calreticulin in functioning of mitochondrial ATP-dependent potassium channel PMID: 25730969
    3. distribution of the cell-specific markers, calretinin and calbindin, in reelin-immunoreactive cells during postnatal rat and mouse neocortical development PMID: 24134921
    4. The stress of maternal deprivation has a significant effect on calretinin and calbindin expression in both male and female ratss, but affects glucocorticoid receptor levels only in males. PMID: 21835217
    5. An essential property of calretinin action potentials is a delayed equilibration with divalent calcium ions. PMID: 21394464
    6. study concludes that, in inner and outer enamel epithelial cells, Ca(2+)is regulated by calbindin, parvalbumin and calretinin during tooth development; in epithelial rests of Malassez of adult periodontal ligament, Ca(2+) is regulated only by calretinin PMID: 21080000
    7. CR mRNA production after TMT treatment could hypothetically be regarded as a compensatory phenomenon in developing rats. PMID: 11834306
    8. Calretinin-positive cells predominantly comprise caudally or locally projecting, possibly glutamatergic basal forebrain neurons PMID: 12577320
    9. CR-IR cells of the neostriatum are a distinct subclass of interneurons that are born at an intermediate time during striatal development and share common neurogenesis characteristics with other interneurons. PMID: 14730585
    10. These data clearly show that expression of CR gene in neurons and cancer cells is regulated by different mechanisms. On the other hand, in both cell types, the activity of CR gene promoter can be stimulated by zinc ions. PMID: 15093134
    11. In rats, calretinin-containing calyces were irregularly interspersed with calretinin-negative calyces and The percentage of calretinin-positive calyces increased during development, to about 75% and 20% at P30 PMID: 15355314
    12. Data show that virtually all newly produced striatal neurons are calretinin (CR)-immunoreactive (+), but not DARPP-32(+), calbindin-D-28K(+), parvalbumin(+), somatostatin(+), or choline acetyltransferase(+). PMID: 18720478

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  • 蛋白家族：
    Calbindin family
  • 数据库链接：

    KEGG: rno:117059

    STRING: 10116.ENSRNOP00000022943

    UniGene: Rn.10321