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  4. Recombinant Rat Dyslexia susceptibility 1 candidate gene 1 protein homolog (Dyx1c1)

Recombinant Rat Dyslexia susceptibility 1 candidate gene 1 protein homolog (Dyx1c1)

  • 中文名称：
    大鼠Dnaaf4重组蛋白
  • 货号：
    CSB-YP722781RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Dnaaf4重组蛋白
  • 货号：
    CSB-EP722781RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Dnaaf4重组蛋白
  • 货号：
    CSB-EP722781RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Dnaaf4重组蛋白
  • 货号：
    CSB-BP722781RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Dnaaf4重组蛋白
  • 货号：
    CSB-MP722781RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Dnaaf4
  • Uniprot No.：
  • 别名：
    Dnaaf4; Dyx1c1; Ekn1Dynein assembly factor 4; axonemal; Dyslexia susceptibility 1 candidate gene 1 protein homolog
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-420
  • 氨基酸序列
    MPVRVSEFSW QQTPAALFLS LPLRGVCVRD ADVFCGESYL KVNFPPFLFE VFLYAPIDDG KSKAKIGNDT ILFTLYKKEP VLWESLSMPG VDKEMMQRIR EKSILQAQEK AKEATEAKAA AKREDQRYAL GEMMKIEEEE RKKIEDMKEN ERKKATRELE AWKECQKKAD GQKRVQRKEK PLQGKQAEER GALKPQSLPR KAPPTRLPTR GRNWENIFSE KLKEDRVPAP RSAGSIQISF TPRVFPTALR ESQVAEEEEW LHKQAEARRA MSTDLPEFSD LKEEEKNPDW LKDKGNKLFA TENYLAAIDA YNLAIRLNRK IPVLYLNRAA CHLKLKNLHK AIEDSSKALE LLTPPVADNA NARMKAHVRR GTAFCQLELY VEGLQDYEAA LKIDPANTVV QNDAEKIRNI IQGTTLKSHD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. Axonemal dynein assembly factor required for ciliary motility.
  • 基因功能参考文献：
    1. Study describes the impact of Dyx1c1 on behavioral functions similar to those affected in language-impaired populations as well as information about changes to the brain following early disruption of this candidate dyslexia susceptibility gene PMID: 23594585
    2. Transfection with Dyx1c1 small hairpin shRNA results from both cell autonomous and non-cell autonomous effects. There is no evidence to support non-cell autonomous disruption of neuronal position in the cerebral cortex itself. PMID: 21070838
    3. These results provide further support for the role of Dyx1c1 in neuronal migration and working memory PMID: 20977651
  • 亚细胞定位：
    Nucleus. Cytoplasm. Cell projection, neuron projection. Dynein axonemal particle.
  • 数据库链接：

    KEGG: rno:363096

    STRING: 10116.ENSRNOP00000029714

    UniGene: Rn.99120