Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Rat Fibrinogen gamma chain (Fgg)

Recombinant Rat Fibrinogen gamma chain (Fgg)

  • 货号：
    CSB-YP008651RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP008651RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP008651RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP008651RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP008651RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Fgg; Fibrinogen gamma chain
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    26-445
  • 氨基酸序列
    QYTAT RDNCCILDER FGSYCPTTCG ISDFLNSYQT DVDTDLQTLE NILQRAENRT TEAKELIKAI QVYYNPDQPP KPGMIEGATQ KSKKMVEEIL KYEALLLTHE SSIRYLQDIY TSNKQKITNL KQKVAQLEAQ CQEPCKDSVR IHDTTGKDCQ DIANKGAKES GLYFIRPLKA TQQFLVYCEI DGSGNGWTVL QKRLDGSVDF KKNWIQYKEG FGHLSPTGTT EFWLGNEKIH LISMQSTIPY ALRIQLKDWS GRTSTADYAM FRVGPESDKY RLTYAYFIGG DAGDAFDGYD FGDDPSDKFF TSHNGMHFST WDNDNDKFEG NCAEQDGSGW WMNKCHAGHL NGVYYQGGTY SKSSTPNGYD NGIIWATWKT RWYSMKETTM KIIPFNRLSI GDGQQHHMGG SKQVSVEHEV DVEYP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
  • 基因功能参考文献：
    1. Changes in macrophage IL-18 and vascular fibrinogen deopsition following injury in aging rats contribute to local inflammation and postinjury neointima formation. PMID: 24414074
    2. FGG dimerization increased on day 6 of pregnancy, dependent on the presence of a developing blastocyst PMID: 21448983
  • 亚细胞定位：
    Secreted.
  • 数据库链接：

    KEGG: rno:24367

    STRING: 10116.ENSRNOP00000032735

    UniGene: Rn.1702