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  4. Recombinant Rat Forkhead box protein J1 (Foxj1)

Recombinant Rat Forkhead box protein J1 (Foxj1)

  • 货号：
    CSB-YP714120RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP714120RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP714120RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP714120RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP714120RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Foxj1
  • Uniprot No.：
  • 别名：
    Foxj1; Hfh4Forkhead box protein J1; Hepatocyte nuclear factor 3 forkhead homolog 4; HFH-4
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-421
  • 氨基酸序列
    MAESWLRLCG AGPGEEAGPE GGMEEPDALD DSLTSLQWLQ EFSILNAKAP TLPPGGTDPL GYHQVPGLVA PGSPLAADPA CLGQPHTPGK PTSSCTSRSA PPGLQAPPPD DVDYATNPHV KPPYSYATLI CMAMQASKAT KITLSAIYKW ITDNFCYFRH ADPTWQNSIR HNLSLNKCFI KVPREKDEPG KGGFWRIDPQ YAERLLSGAF KKRRLPPVHI HPAFARQAAQ EPSTAPWGGP LTVNREAQQL LQEFEEATGE GGWGTGEGRL GHKRKQPLPK RVAKVLRPPS TLLLTQEEQG ELEPLKGNFD WEAIFEAGAL GEELSSLEGL ELSPPLSPSS HGEVDLTVHG RHINCPATWG PPVEQATDSL DFDETFLATS FLQHPWDESS SGCLPPEPLF EAGDATLAAD LQDWASVGAF L
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor specifically required for the formation of motile cilia. Acts by activating transcription of genes that mediate assembly of motile cilia, such as CFAP157. Binds the DNA consensus sequences 5'-HWDTGTTTGTTTA-3' or 5'-KTTTGTTGTTKTW-3' (where H is not G, W is A or T, D is not C, and K is G or T). Activates the transcription of a variety of ciliary proteins in the developing brain and lung.
  • 基因功能参考文献：
    1. peripheral nerve crush-induced up-regulation of Foxj1 in the sciatic nerve was associated with Schwann cells proliferation. PMID: 23515839
    2. The findings of this study suggested that FOXJ1 plays an important role on neuronal production and neurogenesis in the adult brain after cerebral ischemia PMID: 23603178
    3. Data suggest that Foxj1 may be involved in the pathophysiology of the brain after traumatic brain injury. PMID: 21347518
    4. Data show that, although estradiol stimulates differentiation of epithelial cells, foxj1 but not estrogen receptor alpha is required for epithelial cell ciliogenesis of the neonatal oviduct. PMID: 15171704
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    FOXJ1 family
  • 组织特异性：
    Pulmonary epithelium, testis and oviduct.
  • 数据库链接：

    KEGG: rno:116557

    UniGene: Rn.202954