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  4. Recombinant Rat Guanine nucleotide-binding protein-like 3 (Gnl3)

Recombinant Rat Guanine nucleotide-binding protein-like 3 (Gnl3)

  • 中文名称：
    大鼠Gnl3重组蛋白
  • 货号：
    CSB-YP770522RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Gnl3重组蛋白
  • 货号：
    CSB-EP770522RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Gnl3重组蛋白
  • 货号：
    CSB-EP770522RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Gnl3重组蛋白
  • 货号：
    CSB-BP770522RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Gnl3重组蛋白
  • 货号：
    CSB-MP770522RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Gnl3
  • Uniprot No.：
  • 别名：
    Gnl3; NsGuanine nucleotide-binding protein-like 3; Nucleolar GTP-binding protein 3; Nucleostemin
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-538
  • 氨基酸序列
    MKRPKLKKAS KRMTCHKRYK IQKKVREHHR KLRKEAKKRG HKKPKKDPGV PNSAPFKEAL LREAELRKQQ LEELKQQQKL DRQKEQERKR KLEISPDDEQ SNVETQEESD EPKIKKAKSG KQNPKKLHCQ ELKKVIEASD IVLEVLDARD PLGCRCPQVE EAVIQSGCKK LVLVLNKSDL VPKENLENWL TYLNKELPTV VFKASTNLKN RKKTFKIKKK VVPFQSKLCC GKEALWKLLG GFQQSCGKGV QVGVVGFPNV GKSSIINSLK QERICSVGVS MGLTRSMQIV PLDKQITIID SPCFIISPCN SPAALALRSP ASIEVLRPLE AASAILSQAD SQQVVLKYTV PGYKDSLDFF TKLAQRRGLH QKGGSPNVES AAKLLWSEWT GASLGYYCHP PASWNHSPHF NENITAIMKR GFNLEELEKN NAHSIQVLKG PHLTNKILFR SSGLTNGILE EKDIPEESPK QTEDQQDGDD QEHVTGEKNA EISDVTPVEE TREMSPGQST ASKPSDRSFI LDKMSEEDDA YDFTTDYI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.
  • 基因功能参考文献：
    1. In summary, this report suggested that Nucleostemin may exert the anti-apoptotic effect through Nucleostemin-p53 signaling pathway after myocardial reperfusion injury. PMID: 26138242
    2. analysis of nucleolar localization of stem cell protein nucleostemin PMID: 15857956
    3. Results suggest that nucleostemin, but not Oct-4 or Nanog, is expressed in bone marrow stromal cells where it possibly regulates self-renewal cell proliferation. PMID: 16139428
    4. cell cycle arrest/inhibitory role of nucleostemin is unlikely to be related to its proposed property of interaction with p53 PMID: 18211284
  • 亚细胞定位：
    Nucleus. Nucleus, nucleolus.
  • 蛋白家族：
    TRAFAC class YlqF/YawG GTPase family
  • 组织特异性：
    Expressed in testis.
  • 数据库链接：

    KEGG: rno:290556

    STRING: 10116.ENSRNOP00000035860

    UniGene: Rn.4110