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  4. Recombinant Rat Interferon-induced guanylate-binding protein 2 (Gbp2)

Recombinant Rat Interferon-induced guanylate-binding protein 2 (Gbp2)

  • 货号：
    CSB-YP717403RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP717403RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP717403RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP717403RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP717403RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Gbp2Guanylate-binding protein 1; EC 3.6.5.-; GTP-binding protein 2; GBP-2; Guanine nucleotide-binding protein 2; Interferon-induced guanylate-binding protein 2; p67
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-586
  • 氨基酸序列
    MASEIHMLQP MCLIENTEAH LVINQEALRI LSAINQPVVV VAIVGLYRTG KSYLMNKLAG KRTGFSLGST VQSHTKGIWM WCVPHPKKAG QTLVLLDTEG LEDVEKGDNQ NDCWIFALAV LLSSTFVYNS MGTINQQAMD QLHYVTELTD LIKSKSSPDQ SGIDDSANFV GFFPTFVWAL RDFSLELEVN GKLVTPDEYL EHSLTLKKGA DKKTKSFNEP RLCIRKFFPK RKCFIFDRPA LRKQLCKLET LGEEELCSEF VEQVAEFTSY IFSYSAVKTL SGGIIVNGPR LKSLVQTYVG AISSGSLPCM ESAVLTLAQI ENSAAVQKAI THYEEQMNQK IQMPTETLQE LLDLHRLIER EAIEIFLKNS FKDVDQKFQT ELGNLLISKR DAFIKKNSDV SSAHCSDLIE DIFGPLEEEV KQGTFSKPGG YFLFLQMRQE LEKKYNQAPG KGLEAEAVLK KYFESKEDIV ETLLKTDQSL TEAAKEIEVE RIKAETAEAA NRELAEKQEK FELMMQQKEE SYQEHVRQLT EKMKEEQKKL IEEQDNIIAL KLREQEKFLR EGYENESKKL LREIENMKRR QSPGKC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.
  • 基因功能参考文献：
    1. Neuronal cells overexpressing GBP2 exhibited up-regulation of GBP2 in the cerebral cortex following traumatic brain injury. PMID: 28239766
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus membrane. Membrane; Lipid-anchor.
  • 蛋白家族：
    TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3-type GTPase family, GB1 subfamily
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    KEGG: rno:171164

    STRING: 10116.ENSRNOP00000061437

    UniGene: Rn.25736