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  4. Recombinant Rat Nuclear RNA export factor 1 (Nxf1)

Recombinant Rat Nuclear RNA export factor 1 (Nxf1)

  • 货号：
    CSB-YP016218RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP016218RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP016218RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP016218RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP016218RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Nxf1
  • Uniprot No.：
  • 别名：
    Nxf1; Tap; Nuclear RNA export factor 1; Tip-associated protein; Tip-associating protein; mRNA export factor TAP
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-618
  • 氨基酸序列
    ADEGKSYNE HDDRVSFPQR RKKGRGPFRW KCGVGNRRSG RGGSGIRSSR FEEDDGDVAM NDPQDGPRVR FNPYTTRPNR RRDTWHDRDR IHVTVRRDRA PQERGGAGTS QDGTTKNWFK ITIPYGKKYD KMWLLSMIQS KCSVPFNPIE FHYENTRAHF FVENATTASA LKAVNYKIQD RENGRISIII NSSAPPYIVQ NELKPEQVEQ LKLIMSKRYD GSQQALDLKG LRSDPDLVAQ NIDVVLNRRG CMAAALRIIE ENIPELLSLN LSNNRLYKLD DMSSIVQKAP NLKILNLSGN ELKSEWELDK IKGLKLEELW LDRNPMCDTF LDQSTYISTI RERFPKLLRL DGHELPPPIA FDVEAPTMLP PCKGSYFGTE NLKSLVLHFL QQYYAIYDSG DRQGLLDAYH DGACCSLSTP SNPQNPVRHN LAKYFNDSRN VKKIKDTTTR FRLLKHTRLN VVAFLNELPK THHDVNSFVV DISAQTSTLL CFSVNGVFKE VDGKSRDSLR AFTRTFIAVP ASNSGLCIVN DELFVRNASP EEIQRAFAMP APTPSSSPVP TLSQEQQDML QAFSTQSGMN LEWSQKCLQD NNWDYTRSAQ AFTHLKAKGE IPEVAFMK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export. Also involved in nuclear export of m6A-containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export.
  • 亚细胞定位：
    Nucleus, nucleoplasm. Nucleus speckle. Nucleus, nuclear pore complex. Nucleus envelope. Cytoplasm. Cytoplasm, Stress granule.
  • 蛋白家族：
    NXF family
  • 数据库链接：

    KEGG: rno:59087

    STRING: 10116.ENSRNOP00000026033

    UniGene: Rn.159847