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  4. Recombinant Rat Nuclear receptor corepressor 1 (Ncor1)

Recombinant Rat Nuclear receptor corepressor 1 (Ncor1)

  • 中文名称：
    大鼠Ncor1重组蛋白
  • 货号：
    CSB-YP893887RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Ncor1重组蛋白
  • 货号：
    CSB-EP893887RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Ncor1重组蛋白
  • 货号：
    CSB-EP893887RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Ncor1重组蛋白
  • 货号：
    CSB-BP893887RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Ncor1重组蛋白
  • 货号：
    CSB-MP893887RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Ncor1; Nuclear receptor corepressor 1; N-CoR; N-CoR1; Fragment
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-533
  • 氨基酸序列
    KDKGPPPKSR YEEELRTRGK TTITAANFID VIITRQIASD KDARERGSQS SDSSSSLSSH RYEAPSDAIE VISPASSPAP PQEKPQTYQP EMVKANQAEN ESPQQYEGPL THYRSQQGSP SPQQQPPLPP SSQAEGMGQV PRTHRLITLA DHICQIITQD FARNQVPSQP STSTFQTSPS ALSSTPVRTK PSSRYSPESQ SQTVLHPRPG PRVSPENLVD KSRGSRPGKS PERSHIPSEP YEPISPPQGP AVHEKQDSML LLSQRGMDPA EQRSDSRSPG SISYLPYFFT KLESTSPMVK SKKQEIFRKL NSSGGGDSDM AAAQPGTEIF NLPAVTTSGA VSSRSHSFAD PASNLGLEDI IRKALMGSFD DKVEDHGVVM PHPVGVVPGS ASTSVVTSSE TRRDEGDPSP HSGVCKPKLI NKSNSRKSKS PIPGQNYLGT ERPSSVSSVH SEGDYHRQTP GWAWEDRPSS TGSTQFPYNP LTIRMLSSTP PTPIACAPSA ITQAAPHQQS RIWEREPAPL LSAQYETLSD SDD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation. Mediates the NR1D1-dependent repression and circadian regulation of TSHB expression. The NCOR1-HDAC3 complex regulates the circadian expression of the core clock gene ARTNL/BMAL1 and the genes involved in lipid metabolism in the liver.
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    N-CoR nuclear receptor corepressors family
  • 数据库链接：

    UniGene: Rn.24948