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  4. Recombinant Rat Nucleolar and coiled-body phosphoprotein 1 (Nolc1)

Recombinant Rat Nucleolar and coiled-body phosphoprotein 1 (Nolc1)

  • 中文名称：
    大鼠Nolc1重组蛋白
  • 货号：
    CSB-YP015929RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Nolc1重组蛋白
  • 货号：
    CSB-EP015929RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Nolc1重组蛋白
  • 货号：
    CSB-EP015929RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Nolc1重组蛋白
  • 货号：
    CSB-BP015929RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Nolc1重组蛋白
  • 货号：
    CSB-MP015929RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Nolc1
  • Uniprot No.：
  • 别名：
    Nolc1; Nucleolar and coiled-body phosphoprotein 1; 140 kDa nucleolar phosphoprotein; Nopp140; Nucleolar 130 kDa protein; Nucleolar phosphoprotein p130
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-704
  • 氨基酸序列
    MADTGLRRVV PSDLYPLVLG FLRDNQLSEV ASKFAKATGA TQQDANASSL LDIYSFWLKS TKAPKVKLQS NGPVAKKAKK ETSSSDSSED SSEEEDKAQV PTQKAAAPAK RASLPQHAGK AAAKASESSS SEESSEEEEE KDKKKKPVQQ KAVKPQAKAV RPPPKKAESS ESESDSSSED EAPQTQKPKA AATAAKAPTK AQTKAPAKPG PPAKAQPKAA NGKAGSSSSS SSSSSSDDSE EEKKAAAPLK KTAPKKQVVA KAPVKVTAAP TQKSSSSEDS SSEEEEEQKK PMKKKAGPYS SVPPPSVSLS KKSVGAQSPK KAAAQTQPAD SSADSSEESD SSSEEEKKTP AKTVVSKTPA KPAPVKKKAE SSSDSSDSDS SEDEAPAKPV SATKSPLSKP AVTPKPPAAK AVATPKQPAG SGQKPQSRKA DSSSSEEESS SSEEEATKKS VTTPKARVTA KAAPSLPAKQ APRAGGDSSS DSESSSSEEE KKTPPKPPAK KKAAGAAVPK PTPVKKAAAE SSSSSSSSED SSEEEKKKPK SKATPKPQAG KANGVPASQN GKAGKESEEE EEDTEQNKKA AGTKPGSGKK RKHNETADEA ATPQSKKVKL QTPNTFPKRK KGEKRASSPF RRVREEEIEV DSRVADNSFD AKRGAAGDWG ERANQVLKFT KGKSFRHEKT KKKRGSYRGG SISVQVNSVK FDSE
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification. Involved in nucleologenesis, possibly by playing a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities.
  • 基因功能参考文献：
    1. These data show that Nopp140 reversibly associates with snoRNPs in a phosphorylation-dependent manner, but this association has no effect on pseudouridylation of rRNA. PMID: 12446766
  • 亚细胞定位：
    Cytoplasm. Nucleus, nucleolus.
  • 数据库链接：

    KEGG: rno:64896

    STRING: 10116.ENSRNOP00000025788

    UniGene: Rn.9517