Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Rat Protein BEX3 (Ngfrap1)

Recombinant Rat Protein BEX3 (Ngfrap1)

  • 货号：
    CSB-YP764785RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP764785RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP764785RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP764785RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP764785RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Bex3; Nade; Ngfrap1Protein BEX3; Brain-expressed X-linked protein 3 homolog; rBex3; Nerve growth factor receptor-associated protein 1; p75NTR-associated cell death executor
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-130
  • 氨基酸序列
    MANIHQENEE MEQPLQNGQE DRPVGGGEGH QPAANNNNHN HNHNHNHNHN HNHHRRGQAR RLAPNFRWAI PNRQMNDGLG GDGDDMEMFM EEMREIRRKL RELQLRNCLR ILMGELSNHH DHHDEFCLMP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death.
  • 基因功能参考文献：
    1. Bex3 has an important role for the regulation of TrkA expression in neurons. PMID: 25948268
    2. Reducing neuronal p75NTR expression plays a critical role in switching satellite glial cells to a reactive state. PMID: 24616056
    3. Expression of p75NTR increased in glia, but was downregulated in sensory neurons in sciatic nerve injury and spinal cord injury. PMID: 19141972
    4. Expression of p75NTR on cholinergic interneurons of the rat striatum is associated with delayed neuronal degeneration. PMID: 12377384
    5. hamartin binds to NADE to regulate neuronal cell function and loss of this association is likely to contribute to the brain pathology in tuberous sclerosis complex PMID: 17355907

    显示更多

    收起更多

  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    BEX family
  • 组织特异性：
    In cochlea, it is expressed in pillar cells from postnatal day 2 to adulthood.
  • 数据库链接：

    KEGG: rno:117089

    STRING: 10116.ENSRNOP00000042696

    UniGene: Rn.3126