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  4. Recombinant Rat Slit homolog 2 protein (Slit2)

Recombinant Rat Slit homolog 2 protein (Slit2)

  • 中文名称：
    大鼠Slit2重组蛋白
  • 货号：
    CSB-YP894839RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Slit2重组蛋白
  • 货号：
    CSB-EP894839RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Slit2重组蛋白
  • 货号：
    CSB-EP894839RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Slit2重组蛋白
  • 货号：
    CSB-BP894839RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Slit2重组蛋白
  • 货号：
    CSB-MP894839RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Slit2
  • Uniprot No.：
  • 别名：
    Slit2; Slit homolog 2 protein; Slit-2; Fragment
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    31-766
  • 氨基酸序列
    QCSCSGSTVD CHGLALRIVP RNIPRNTERL DLNGNNITRI TKTDFAGLRH LRILQLMENK ISTIERGAFH DLKELERLRL NRNNLQLFPE LLFLGTAKLY RLDLSENQIQ AIPRKAFRGA VDIKNLQLDY NQISCIEDGA FRALRDLEVL TLNNNNITRL SVASFNHMPK LRTFRLHSNN LYCDCHLAWL SDWLRQRPRV GLYTQCMGPS HLRGHNVAEV QKREFVCSDE EEGHQSFMAP SCSVLHCPIA CTCSNNIVDC RGKGLTEIPT NLPETITEIR LEQNSIRVIP PGAFSPYKKL RRLDLSNNQI SELAPDAFQG LRSLNSLVLY GNKITELPKS LFEGLFSLQL LLLNANKINC LRVDAFQDLH NLNLLSLYDN KLQTVAKGTF SALRAIQTMH LAQNPFICDC HLKWLADYLH TNPIETSGAR CTSPRRLANK RIGQIKSKKF RCSGTEDYRS KLSGDCFADL ACPEKCRCEG TTVDCSNQKL NKIPDHIPQY TAELRLNNNE FTVLEATGIF KKLPQLRKIN LSNNKITDIE EGAFEGASGV NEILLTSNRL ENVQHKMFKG LESLKTLMLR SNRISCVGND SFTGLGSVRL LSLYDNQITT VAPGAFGTLH SLSTLNLLAN PFNCNCHLAW LGEWLRRKRI VTGNPRCQKP YFLKEIPIQD VAIQDFTCDD GNDDNSCSPL SRCPSECTCL DTVVRCSNKG LKVLPKGIPR DVTELYLDGN QFTLVP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. Seems to be involved in regulating leukocyte migration.
  • 亚细胞定位：
    Secreted.
  • 数据库链接：

    STRING: 10116.ENSRNOP00000005477

    UniGene: Rn.146652