Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Rat Sodium-dependent phosphate transporter 2 (Slc20a2), partial

Recombinant Rat Sodium-dependent phosphate transporter 2 (Slc20a2), partial

  • 中文名称：
    大鼠Slc20a2重组蛋白
  • 货号：
    CSB-YP717381RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Slc20a2重组蛋白
  • 货号：
    CSB-EP717381RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Slc20a2重组蛋白
  • 货号：
    CSB-EP717381RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Slc20a2重组蛋白
  • 货号：
    CSB-BP717381RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Slc20a2重组蛋白
  • 货号：
    CSB-MP717381RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Slc20a2
  • Uniprot No.：
  • 别名：
    Slc20a2; Pit2; Ram1; Sodium-dependent phosphate transporter 2; Phosphate transporter 2; PiT-2; Receptor for amphotropic viruses 1; RAM-1; Solute carrier family 20 member 2
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not significantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. Functions as a retroviral receptor.
  • 基因功能参考文献：
    1. Results describe the regulation of the sodium/phosphate cotransporters SCL34A3 and SLC20A2 during phosphate deprivation and acidosis in rat kidney. PMID: 19841935
    2. mRNA expression level of Glvr-2 was increased by the addition of inorganic phosphate (Pi) in bone marrow stromal cells PMID: 14584042
    3. PiT-1 (Slc20a1) and PiT-2 (Slc20a2) were detected at the basolateral membrane of hepatocytes. PMID: 15564340
    4. We have used RNA interference to demonstrate that Pit1 and Pit2 are the transporters responsible for Na-dependent Pi transport in VSMCs. PMID: 17322102
    5. The Na+-Pi cotransporter PiT-2 (SLC20A2) is expressed in the apical membrane of rat renal proximal tubules and regulated by dietary Pi. PMID: 19073637

    显示更多

    收起更多

  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Inorganic phosphate transporter (PiT) (TC 2.A.20) family
  • 组织特异性：
    Widely expressed with highest levels in liver, heart and brain.
  • 数据库链接：

    KEGG: rno:29502

    STRING: 10116.ENSRNOP00000026418

    UniGene: Rn.13642