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  4. Recombinant Rat Stanniocalcin-1 (Stc1)

Recombinant Rat Stanniocalcin-1 (Stc1)

  • 中文名称：
    大鼠Stc1重组蛋白
  • 货号：
    CSB-YP022821RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Stc1重组蛋白
  • 货号：
    CSB-EP022821RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Stc1重组蛋白
  • 货号：
    CSB-EP022821RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Stc1重组蛋白
  • 货号：
    CSB-BP022821RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Stc1重组蛋白
  • 货号：
    CSB-MP022821RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Stc1
  • Uniprot No.：
  • 别名：
    Stc1; Stc; Stanniocalcin-1; STC-1
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    34-247
  • 氨基酸序列
    VAAQNSA EVVRCLNSAL QVGCGAFACL ENSTCDTDGM YDICKSFLYS AAKFDTQGKA FVKESLKCIA NGITSKVFLA IRRCSTFQRM IAEVQEDCYS KLNVCSIAKR NPEAITEVIQ LPNHFSNRYY NRLVRSLLEC DEDTVSTIRD SLMEKIGPNM ASLFHILQTD HCAQTHPRAD FNRRRTNEPQ KLKVLLRNLR GEGDSPSHIK RTSQENA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia.
  • 基因功能参考文献：
    1. Results show that STC1 have an important role in the carbohydrate metabolism regulation, in particular gluconeogenesis from glutamine in the kidney, across the vertebrates. PMID: 26187698
    2. Stanniocalcin-1 (STC-1) within the subfornical organ may act in a paracrine/autocrine manner to modulate the neuronal responses to blood-borne angiotensin II. PMID: 22933020
    3. STC1 gene induction proceeds through cyclic AMP and ERK1/2, independently of protein kinase A, the canonical cAMP effector. PMID: 21975601
    4. Endogenous STC-1 signaling in nucleus solitarius is involved in regulating the excitability of neurons functioning as components of the baroreceptor reflex controlling arterial pressure. PMID: 22343086
    5. the inner medullary STC-1 gene is differentially regulated in rat and mouse by arginine vasopressin and angiotensin II PMID: 21867741
    6. The findings are therefore indicative of cortical and medullary STC-1 having separate roles in the renal control of extracellular fluid balance. PMID: 20887770
    7. STC1 accelerates osteoblast development in an autocrine/paracrine manner in the rat calvaria cell culture model. PMID: 12933688
    8. role for mammalian STC1 in modulating the immune/inflammatory response in ureteric obstruction PMID: 14570698
    9. Stanniocalcin 1 acts as a paracrine regulator of growth plate chondrogenesis PMID: 16377640
    10. This study provides the first evidence of the regulation of STC1 expression in the male reproductive system. PMID: 18187254
    11. The endogenous STC-1, similar to milk-derived STC-1, may be involved in digestion and/or absorption in gastrointestinal organs. PMID: 19732741

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Stanniocalcin family
  • 数据库链接：

    KEGG: rno:81801

    STRING: 10116.ENSRNOP00000020728

    UniGene: Rn.10647