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  4. Recombinant Rat Synaptobrevin homolog YKT6 (Ykt6)

Recombinant Rat Synaptobrevin homolog YKT6 (Ykt6)

  • 货号：
    CSB-YP707844RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP707844RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP707844RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP707844RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP707844RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ykt6
  • Uniprot No.：
  • 别名：
    Ykt6Synaptobrevin homolog YKT6; EC 2.3.1.-
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-195
  • 氨基酸序列
    MKLYSLSVFY KGEPKAVLLK AAYDVSSFSF FQRSSVQEFM TFTSQLIVER SAKGSRASVK EQEYLCHVYV RSDSLAGVVI ADSEYPSRVA FTLLEKVLDE FSKQVDRIDW PVGSPATIHY TALDGHLSRY QNPREADPMS KVQAELDETK IILHNTMESL LERGEKLDDL VSKSEVLGTQ SKAFYKTARK QNSCC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.
  • 基因功能参考文献：
    1. Dodecylphosphocholine-regulated intramolecular conformational dynamics of Ykt6 has been reported. PMID: 27493064
    2. The ykt6 particles/aggregates may represent ykt6 engaged in a non-SNARE function(s) or else nonfunctional, stored and/or excess ykt6. PMID: 22443861
    3. A posttranslationally attached farnesyl group can actively regulate Ykt6 fusion activity in addition to its anticipated membrane-anchoring role. PMID: 20159557
    4. ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain PMID: 12589064
    5. The Ykt6 intramolecular interactions would be predicted to create a compact, closed conformation of the SNARE that prevents promiscuous targeting interactions and premature insertion into membranes. PMID: 15331663

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  • 亚细胞定位：
    Cytoplasm, cytosol. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Synaptobrevin family
  • 组织特异性：
    Highly expressed by neurons in brain and faintly detected in spleen, lung and kidney (at protein level). Ubiquitously expressed.
  • 数据库链接：

    KEGG: rno:64351

    STRING: 10116.ENSRNOP00000020693

    UniGene: Rn.6525