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  4. Recombinant Rat Urotensin-2B (Uts2d)

Recombinant Rat Urotensin-2B (Uts2d)

  • 货号：
    CSB-YP762313RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP762313RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP762313RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP762313RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP762313RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Uts2b
  • Uniprot No.：
  • 别名：
    Uts2b; Urp; Uts2d; Urotensin-2B; Urotensin II-related peptide; Urotensin IIB; U-IIB; UIIB; Urotensin-2 domain-containing protein
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Cytoplasmic domain
  • 表达区域：
    111-118
  • 氨基酸序列
    ACFWKYCV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Potent vasoconstrictor.
  • 基因功能参考文献：
    1. URP is the endogenous and functional ligand for UII receptor in the rat PMID: 14550283
    2. central urotensin II may play a role in the pathogenesis of hypertension in SHR rats PMID: 14621188
    3. URP is the endogenous and functional ligand for urotensin II receptor in the rat. (REVIEW) PMID: 15476951
    4. The long-lasting vasoconstriction induced by hU-II alone is PKC dependent and associated with PKC-theta phosphorylation. PMID: 16951045
    5. Data suggest that the expression of urotensin II-related peptide, urotensin II and urotensin II receptor is enhanced in failing heart, and the UII/URP/UT-R system has important pathophysiological roles in the progression of heart failure. PMID: 18314225
    6. SHR are more sensitive than WKY rats to UII, which acts primarily to lower glomerular filtration rate thus favoring salt retention in this model of hypertension PMID: 18701623
    7. Increased expression of urotensin II-related peptide in kidney with hypertension or renal failure PMID: 18955095
    8. In the aorta, expression levels of urotensin II-related peptide mRNA was significantly elevated in 11-12-week-old SHR compared with age-matched WKY, similarly to those in the kidney. PMID: 19463745

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Urotensin-2 family
  • 组织特异性：
    Expressed in a number of tissues includinf brain, thymus, spleen, testis and spinal cord.
  • 数据库链接：

    KEGG: rno:378939

    STRING: 10116.ENSRNOP00000039320

    UniGene: Rn.105611