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  4. Recombinant Rat ZW10 interactor (Zwint)

Recombinant Rat ZW10 interactor (Zwint)

  • 中文名称：
    大鼠Zwint重组蛋白
  • 货号：
    CSB-YP855367RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Zwint重组蛋白
  • 货号：
    CSB-EP855367RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Zwint重组蛋白
  • 货号：
    CSB-EP855367RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Zwint重组蛋白
  • 货号：
    CSB-BP855367RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Zwint重组蛋白
  • 货号：
    CSB-MP855367RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Zwint
  • Uniprot No.：
  • 别名：
    Zwint; Sip30; ZW10 interactor; SNAP25-interacting protein 30; Scoilin; ZW10-interacting protein 1; Zwint-1
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-266
  • 氨基酸序列
    MADAEKNAVA EKNAVAEENA VAEENAVADK NATKEVLAEA ASVLEPVGLP EEAELPAKIM EEFMRNSRKK DKLLCSQLQV VNFLQTFLAQ EDNTDQNPDA LASEDTSRQK ATETKEQWKE LKATYMDHVD VIKCALSEAL PQVKEAHRKY TELQKAFEQL EAKKRVLEEK LQLAQKQWVL QQKRLQNLTK ISAEVKRRRK RALEKLDGSH QELETLKQQA GQEQEKLQRN QSYLQLLCSL QNKLVISESK ADDKDVKGPA LPPKSP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.
  • 基因功能参考文献：
    1. our results highlight SIP30 as a target to mediate neuropathic pain-evoked negative emotion PMID: 24403136
    2. there is an ERK-responsive region in the rat sip30 promoter. Activation of ERK promotes the recruitment of the transcription factor cyclic AMP-response element-binding protein to the sip30 gene promoter PMID: 19723624
  • 亚细胞定位：
    Nucleus. Chromosome, centromere, kinetochore.
  • 组织特异性：
    Expressed abundantly in brain and at lower levels in testis and kidney.
  • 数据库链接：

    KEGG: rno:257644

    STRING: 10116.ENSRNOP00000067414

    UniGene: Rn.163272