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  4. Recombinant Saccharomyces cerevisiae AP-1-like transcription activator YAP2 (CAD1)

Recombinant Saccharomyces cerevisiae AP-1-like transcription activator YAP2 (CAD1)

  • 中文名称：
    Recombinant Saccharomyces cerevisiae AP-1-like transcription activator YAP2(CAD1),Yeast
  • 货号：
    CSB-YP326173SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae AP-1-like transcription activator YAP2(CAD1),Yeast
  • 货号：
    CSB-EP326173SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae AP-1-like transcription activator YAP2(CAD1),Yeast
  • 货号：
    CSB-EP326173SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae AP-1-like transcription activator YAP2(CAD1),Yeast
  • 货号：
    CSB-BP326173SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae AP-1-like transcription activator YAP2(CAD1),Yeast
  • 货号：
    CSB-MP326173SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CAD1
  • Uniprot No.：
  • 别名：
    CAD1; YAP2; YDR423C; D9461.12AP-1-like transcription factor YAP2; Cadmium resistance protein 1; Transcription factor CAD1
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-409
  • 氨基酸序列
    MGNILRKGQQ IYLAGDMKKQ MLLNKDGTPK RKVGRPGRKR IDSEAKSRRT AQNRAAQRAF RDRKEAKMKS LQERVELLEQ KDAQNKTTTD FLLCSLKSLL SEITKYRAKN SDDERILAFL DDLQEQQKRE NEKGTSTAVS KAAKELPSPN SDENMTVNTS IEVQPHTQEN EKVMWNIGSW NAPSLTNSWD SPPGNRTGAV TIGDESINGS EMPDFSLDLV SNDRQTGLEA LDYDIHNYFP QHSERLTAEK IDTSACQCEI DQKYLPYETE DDTLFPSVLP LAVGSQCNNI CNRKCIGTKP CSNKEIKCDL ITSHLLNQKS LASVLPVAAS HTKTIRTQSE AIEHISSAIS NGKASCYHIL EEISSLPKYS SLDIDDLCSE LIIKAKCTDD CKIVVKARDL QSALVRQLL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription activator involved in oxidative stress response and cadmium resistance. Regulates the transcription of genes overrepresented for the function of stabilizing proteins including the inducible Hsp90-family protein HSP82. Preferentially binds to promoters with the core binding site 5'-TTA[CG]TAA-3'. Activity of the transcription factor is controlled through oxidation of specific cysteine residues resulting in the alteration of its subcellular location. Activation by alkyl hydroperoxides or cadmium induces nuclear accumulation and as a result CAD1/YAP2 transcriptional activity.
  • 基因功能参考文献：
    1. We conclude that specificity determinants of the Cd response are encoded within both Yap1 and Yap2 C-terminus, whereas those required for H2O2 response are only present in the Yap1 C-terminus. PMID: 17187783
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    BZIP family, YAP subfamily
  • 数据库链接：

    KEGG: sce:YDR423C

    STRING: 4932.YDR423C