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  4. Recombinant Saccharomyces cerevisiae AP-1-like transcription factor YAP4 (CIN5)

Recombinant Saccharomyces cerevisiae AP-1-like transcription factor YAP4 (CIN5)

  • 中文名称：
    Recombinant Saccharomyces cerevisiae AP-1-like transcription factor YAP4(CIN5),Yeast
  • 货号：
    CSB-YP336802SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae AP-1-like transcription factor YAP4(CIN5),Yeast
  • 货号：
    CSB-EP336802SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae AP-1-like transcription factor YAP4(CIN5),Yeast
  • 货号：
    CSB-EP336802SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae AP-1-like transcription factor YAP4(CIN5),Yeast
  • 货号：
    CSB-BP336802SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae AP-1-like transcription factor YAP4(CIN5),Yeast
  • 货号：
    CSB-MP336802SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CIN5
  • Uniprot No.：
  • 别名：
    CIN5; HAL6; SDS15; YAP4; YOR028C; OR26.18; AP-1-like transcription factor YAP4; Chromosome instability protein 5; Transcription activator CIN5
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-295
  • 氨基酸序列
    MLMQIKMDNH PFNFQPILAS HSMTRDSTKP KKMTDTAFVP SPPVGFIKEE NKADLHTISV VASNVTLPQI QLPKIATLEE PGYESRTGSL TDLSGRRNSV NIGALCEDVP NTAGPHIARP VTINNLIPPS LPRLNTYQLR PQLSDTHLNC HFNSNPYTTA SHAPFESSYT TASTFTSQPA ASYFPSNSTP ATRKNSATTN LPSEERRRVS VSLSEQVFNE GERYNNDGQL IGKTGKPLRN TKRAAQNRSA QKAFRQRREK YIKNLEEKSK LFDGLMKENS ELKKMIESLK SKLKE
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription activator involved in the regulation of genes expressed in response to environmental changes and metabolic requirements. According to genome-wide promoter binding and gene expression studies it regulates, among others, genes involved in ribosome biogenesis, and protein synthesis. It may also be involved in pleiotropic drug resistance. When overexpressed it confers increased resistance to cisplatin, the DNA-alkylating agents methylmethanosulfonate, and mitomycin C, the antimalarial drugs quinidine, mefloquine, and chloroquine, and increases cellular tolerance to sodium and lithium. Preferentially binds 5'-TTACTAA-3'.
  • 基因功能参考文献：
    1. Mutant forms of Yap1 that are constitutively trapped in the nucleus are degraded in the absence of an oxidant signal PMID: 22707721
    2. Yap4 activity is maintained in the absence of phosphorylation. However, this modification seems to be required for stability of the protein, as the non-phosphorylated form has a shorter half-life than the phosphorylated one. PMID: 19774548
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    BZIP family, YAP subfamily
  • 数据库链接：

    KEGG: sce:YOR028C

    STRING: 4932.YOR028C