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Recombinant Saccharomyces cerevisiae Metal-binding activator 1 (MAC1)

  • 货号:
    CSB-YP336028SVG
  • 规格:
  • 来源:
    Yeast
  • 其他:
  • 货号:
    CSB-EP336028SVG
  • 规格:
  • 来源:
    E.coli
  • 其他:
  • 货号:
    CSB-EP336028SVG-B
  • 规格:
  • 来源:
    E.coli
  • 共轭:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 货号:
    CSB-BP336028SVG
  • 规格:
  • 来源:
    Baculovirus
  • 其他:
  • 货号:
    CSB-MP336028SVG
  • 规格:
  • 来源:
    Mammalian cell
  • 其他:

产品详情

  • 纯度:
    >85% (SDS-PAGE)
  • 基因名:
    MAC1
  • Uniprot No.:
  • 别名:
    MAC1; CUA1; YMR021C; YM9711.11CMetal-binding activator 1
  • 种属:
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度:
    full length protein
  • 表达区域:
    1-417
  • 氨基酸序列
    MIIFNGNKYA CASCIRGHRS STCRHSHRML IKVRTRGRPS PMAIRDAILV DSTSQSTEYE NGAQIEGDCC SAMNQQPILF VRASAVRKAR MINGKLHILM EEGFTAHEPK DISTFTDDGN KYITETEFLR KHSPKAPATG TISPDSTKSS SSSEKKERSR LQQEPIRHFS NCCKKDKSQN PASNGKTNKA PSDDIFTPYG SLESTSAFND ILQENYNSSV PGAHDSSETL TPQSTTTIAA PHSSDVASKV EVLTHKGIFL STQCSCEDES CPCVNCLIHR SEEELNSYIQ QSGVPLTNIG EAQITDKMMD YLDDCKCTDK ECICPPDNCT CDGCFSHSTN IIPFEKFFFY GILNARLTRK TQIKFKGKLV PSKYWWDFLK LQVPLMTDAQ LELLDIHAWF QKLVSNYAPH LSDATTS
  • 蛋白标签:
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    Regulatory protein involved in Cu/Fe utilization and stress resistance. Involved in basal level transcription of FRE1 and H(2)O(2)-induced transcription of CTT1. Regulates the transcription of CTR1 and CTR3 via the copper ion responsive elements in their promoters. Required for degradation of CTR1.
  • 基因功能参考文献:
    1. these results suggest that Mac1p can activate the expression of vacuolar copper transporter Ctr2p in response to copper deficiency, resulting in yeast resistance to copper starvation. PMID: 22445756
    2. Deletion of the MAC1 and CTR1 genes involved in copper ion homeostasis exhibited freeze-thaw sensitivity, suggesting that copper ion homeostasis is required for freeze-thaw tolerance. PMID: 19749072
  • 亚细胞定位:
    Nucleus.
  • 数据库链接:

    KEGG: sce:YMR021C

    STRING: 4932.YMR021C