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  4. Recombinant Saccharomyces cerevisiae Phosphatidylinositol transfer protein CSR1 (CSR1)

Recombinant Saccharomyces cerevisiae Phosphatidylinositol transfer protein CSR1 (CSR1)

  • 货号：
    CSB-YP313314SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP313314SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP313314SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP313314SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP313314SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CSR1
  • Uniprot No.：
  • 别名：
    CSR1; SFH2; YLR380WPhosphatidylinositol transfer protein CSR1; CHS5 SPA2 rescue protein 1; SEC14 homolog protein 2
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-408
  • 氨基酸序列
    SFDRQLTED QEVVLKQIWT HLFHLWQVPV DGTHIFPNNS LHSSSTPAKK KKSSWFSKLQ SSDHTQDSSE AAEAAHLYEK GKIHKALANL DPQTTKKQFW HDIKNETPDA TILKFIRARK WNADKTIAML GHDLYWRKDT INKIINGGER AVYENNETGV IKNLELQKAT IQGYDNDMRP VILVRPRLHH SSDQTEQELE KFSLLVIEQS KLFFKENYPA STTILFDLNG FSMSNMDYAP VKFLITCFEA HYPESLGHLL IHKAPWIFNP IWNIIKNWLD PVVASKIVFT KNIDELHKFI QPQYIPRYLG GENDNDLDHY TPPDGSLDVH LKDTETRAMI EKEREELVEQ FLTVTAQWIE HQPLNDPAYI QLQEKRVQLS TALCENYSKL DPYIRSRSVY DYNGSLKV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Activates SPO14/PLD1 (phospholipase D1) by stimulating phosphoinositide synthesis via the STT4 PtdIns 4-kinase. Modulates ArfGAP function through effects on SPO14 activity. Inhibits phosphatidylcholine degradation by PLB1 (phospholipase B1). May also regulate post-Golgi membrane-trafficking events and have a role resistance to oxidative stress. Inhibits fatty acid synthase activity in response to heme depletion and oleic acid starvation, preventing saturated fatty acid (SFA) accumulation.
  • 基因功能参考文献：
    1. This review describes how overexpression of Sec14p-like protein SFH2 (Sec Fourteen Homologue 2) rescues sec14-1(temperature-sensitive)-associated growth and secretory defects. PMID: 16709158
    2. Sfh2p inhibits fatty acid synthase activity in response to haem depletion PMID: 17803462
  • 亚细胞定位：
    Cytoplasm. Microsome. Endosome.
  • 蛋白家族：
    PITP family
  • 数据库链接：

    KEGG: sce:YLR380W

    STRING: 4932.YLR380W