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  4. Recombinant Saccharomyces cerevisiae Platinum sensitivity protein 3 (PSY3)

Recombinant Saccharomyces cerevisiae Platinum sensitivity protein 3 (PSY3)

  • 中文名称：
    酿酒酵母PSY3重组蛋白
  • 货号：
    CSB-YP621475SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    酿酒酵母PSY3重组蛋白
  • 货号：
    CSB-EP621475SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    酿酒酵母PSY3重组蛋白
  • 货号：
    CSB-EP621475SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    酿酒酵母PSY3重组蛋白
  • 货号：
    CSB-BP621475SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    酿酒酵母PSY3重组蛋白
  • 货号：
    CSB-MP621475SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PSY3
  • Uniprot No.：
  • 别名：
    PSY3; YLR376C; L8039.17; Platinum sensitivity protein 3
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-242
  • 氨基酸序列
    MEVLKNIRIY PLSNFITSTK NYINLPNELR NLISEEQESK LGFLHIIESD FKPSVALQKL VNCTTGDEKI LIIDIVSIWS QQKQRQHGAI YMNSLSCINI TGLIVFLELL YDSPMDALRR CQVDNFNFQL RGIVIDNLSF LNFESDKNYD VINLSKFEKL FKILRKLREF LGCWIITKSF PTDFYNGIEN TLVDKWSIKR KSGVTLYPTK LPDSYMKGMD LIIYREVVDG RPQYRRIAAL EE
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for resistance to the DNA-damaging agents methyl methanesulfonate (MMS), cisplatin and oxaliplatin, but not to mitomycin C. Plays a role in protection against mutation accumulation. May be a component of the recombination-repair pathway.
  • 基因功能参考文献：
    1. Data indicate that Csm2, Psy3, Shu1 and Shu2 interact with each other in sequence to form a V-shape overall structure in Shu complex. PMID: 29069504
    2. The data suggest a model in which Csm2-Psy3 recruit the Shu complex to homologous recombination substrates, where it interacts with Rad51 through Rad55-Rad57 to stimulate Rad51 filament assembly and stability, promoting error-free repair. PMID: 23460207
    3. analysis of the crystal structure of the Psy3-Csm2 sub-complex PMID: 22749910
    4. the contribution of the ER24 gene product Ylr376Cp and of the two suppressor gene products Yjl185Cp and Yjr129Cp to a complex regulation of the glyoxylate cycle in yeast. PMID: 17146497
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    KEGG: sce:YLR376C

    STRING: 4932.YLR376C