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  4. Recombinant Saccharomyces cerevisiae Suppressor protein STM1 (STM1)

Recombinant Saccharomyces cerevisiae Suppressor protein STM1 (STM1)

  • 中文名称：
    酿酒酵母STM1重组蛋白
  • 货号：
    CSB-YP334507SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    酿酒酵母STM1重组蛋白
  • 货号：
    CSB-EP334507SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    酿酒酵母STM1重组蛋白
  • 货号：
    CSB-EP334507SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    酿酒酵母STM1重组蛋白
  • 货号：
    CSB-BP334507SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    酿酒酵母STM1重组蛋白
  • 货号：
    CSB-MP334507SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    STM1
  • Uniprot No.：
  • 别名：
    STM1; MPT4; STO1; YLR150W; L9634.1; Suppressor protein STM1; 3BP1; GU4 nucleic-binding protein 2; G4p2 protein; POP2 multicopy suppressor protein 4; Ribosomal subunits association factor; AF; TOM1 suppressor protein 1; Triplex-binding protein 1
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-273
  • 氨基酸序列
    SNPFDLLGN DVEDADVVVL PPKEIVKSNT SSKKADVPPP SADPSKARKN RPRPSGNEGA IRDKTAGRRN NRSKDVTDSA TTKKSNTRRA TDRHSRTGKT DTKKKVNQGW GDDKKELSAE KEAQADAAAE IAEDAAEAED AGKPKTAQLS LQDYLNQQAN NQFNKVPEAK KVELDAERIE TAEKEAYVPA TKVKNVKSKQ LKTKEYLEFD ATFVESNTRK NFGDRNNNSR NNFNNRRGGR GARKGNNTAN ATNSANTVQK NRNIDVSNLP SLA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Binds specifically G4 quadruplex (these are four-stranded right-handed helices, stabilized by guanine base quartets) and purine motif triplex (characterized by a third, antiparallel purine-rich DNA strand located within the major groove of a homopurine stretch of duplex DNA) nucleic acid structures. These structures may be present at telomeres or in rRNAs. Acts with CDC13 to control telomere length homeostasis. Involved in the control of the apoptosis-like cell death.
  • 基因功能参考文献：
    1. These findings suggest that Stm1p can act as a ribosome preservation factor under conditions of nutrient deprivation and restoration. PMID: 23206692
    2. Stm1 may recognize the shape of the triplex rather than the base sequence of the triplex. PMID: 18776278
    3. Stm(amino acids 1-113) is the minimal domain to specifically bind with the purine motif triplex. PMID: 18029617
    4. Stm1 loss-of-function alleles and overexpression strains show several genetic interactions with Pat1 and Dhh1 alleles in a manner consistent with Stm1 working upstream of Dhh1 to promote Dhh1 function. PMID: 19015546
    5. data indicates that Stm1p plays a complementary role to eEF3 in translation. PMID: 19666721

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  • 亚细胞定位：
    Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Note=Concentrated in the perinuclear region.
  • 数据库链接：

    KEGG: sce:YLR150W

    STRING: 4932.YLR150W