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  4. Recombinant Schizosaccharomyces pombe ATP-dependent RNA helicase uap56 (uap56)

Recombinant Schizosaccharomyces pombe ATP-dependent RNA helicase uap56 (uap56)

  • 中文名称：
    庞贝裂殖酵母uap56重组蛋白
  • 货号：
    CSB-YP522590SXV
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    庞贝裂殖酵母uap56重组蛋白
  • 货号：
    CSB-EP522590SXV
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    庞贝裂殖酵母uap56重组蛋白
  • 货号：
    CSB-EP522590SXV-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    庞贝裂殖酵母uap56重组蛋白
  • 货号：
    CSB-BP522590SXV
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    庞贝裂殖酵母uap56重组蛋白
  • 货号：
    CSB-MP522590SXV
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    uap56
  • Uniprot No.：
  • 别名：
    uap56; sub2; SPAC17G6.14c; ATP-dependent RNA helicase uap56; EC 3.6.4.13
  • 种属：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-434
  • 氨基酸序列
    MASAQEDLID YEEEEELVQD QPAQEITPAA DTAENGEKSD KKGSYVGIHS TGFRDFLLKP ELLRAITDSG FEHPSEVQQV CIPQSILGTD VLCQAKSGMG KTAVFVLSTL QQIEPVDGEV SVLVLCHTRE LAFQIKNEYA RFSKYLPDVR TAVFYGGINI KQDMEAFKDK SKSPHIVVAT PGRLNALVRE KILKVNSVKH FVLDECDKLL ESVDMRRDIQ EVFRATPPQK QVMMFSATLS NEIRPICKKF MQNPLEIYVD DETKLTLHGL QQHYVKLEEK AKNRKINDLL DSLEFNQVVI FVKSVSRANE LDRLLRECNF PSICIHGGLP QEERIKRYKA FKDFDKRICV ATDVFGRGID IERVNIVINY DMPDSPDSYL HRVGRAGRFG TKGLAITFSS SEEDSQILDK IQERFEVNIT ELPDEIDVGS YMNA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 plays also a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity. Links the mRNA adapter mlo3 to rae1 for targeting mRNA-protein complex to the proteins of the nucleoporin complex (NPC).
  • 基因功能参考文献：
    1. When the TREX components UAP56 or Aly are knocked down, spliced mRNA, as well as total polyA+ RNA, accumulates in nuclear speckle domains. PMID: 20981025
    2. uap56 is required for mRNA transport in S. pombe PMID: 15990877
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    DEAD box helicase family, DECD subfamily
  • 数据库链接：

    KEGG: spo:SPAC17G6.14c

    STRING: 4896.SPAC17G6.14c.1