Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Schizosaccharomyces pombe Target of rapamycin complex 2 subunit bit61 (bit61)

Recombinant Schizosaccharomyces pombe Target of rapamycin complex 2 subunit bit61 (bit61)

  • 中文名称：
    Recombinant Schizosaccharomyces pombe Target of rapamycin complex 2 subunit bit61(bit61),Yeast
  • 货号：
    CSB-YP527939SXV
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Schizosaccharomyces pombe Target of rapamycin complex 2 subunit bit61(bit61),Yeast
  • 货号：
    CSB-EP527939SXV
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Schizosaccharomyces pombe Target of rapamycin complex 2 subunit bit61(bit61),Yeast
  • 货号：
    CSB-EP527939SXV-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Schizosaccharomyces pombe Target of rapamycin complex 2 subunit bit61(bit61),Yeast
  • 货号：
    CSB-BP527939SXV
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Schizosaccharomyces pombe Target of rapamycin complex 2 subunit bit61(bit61),Yeast
  • 货号：
    CSB-MP527939SXV
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    bit61
  • Uniprot No.：
  • 别名：
    bit61; SPCC777.08cTarget of rapamycin complex 2 subunit bit61; TORC2 subunit bit61
  • 种属：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-422
  • 氨基酸序列
    MVGRGSFSST SSASSINWIP KNTKTSIESV SNTISLSENG QNQDLETVTT KESNVGDSDT TENIKSPFNG QWPFSRRSSQ SSSHPVFEET HWSKHSKRPG KLNVLTPTSP SNVNAEVQSI STKTQLSLLN LSPHKHKKPK DGLDLSALQK TLNGSRNFLR GRRDAGGIFG ASIPQSLVTN QIINGFGAAS LAFAKLGKVR SPLEGRFNLV PISADETWLI VESEVCSLYS GEALHYSLED LNGILILHLQ ALIRDTKMNE FVGHLETLFR KATKCLSDSL SPVPEELFLN RIIETWLFFF SSVLPYVQGV FLPIKTKLFD EQEKTQLPYE VNEFCSTNRE KLNVHRLALM TFRDYMVLPI ANRIQICIGR AESAENALDN AGEVFARLFQ ILSLLASVRT NDSKEQEITN LATKVRCLLI AS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of TORC2, which regulates multiple cellular processes to control cell growth in response to environmental signals. TORC2 is required for cell survival under various stress conditions. TORC2 positively controls G1 cell-cycle arrest, sexual development and amino acid uptake. Positively regulates amino acid uptake through the control of expression of amino acid permeases.
  • 基因功能参考文献：
    1. Our work reveals that SAGA is a direct target of nutrient-sensing pathways and has uncovered a mechanism by which TORC1 and TORC2 converge to control gene expression and cell fate decisions. PMID: 29079657
    2. findings highlight the significance of glucose availability in regulation of TORC2-Gad8 and indicate a novel link between the cAMP/PKA, Pmk1/MAPK, and TORC2-Gad8 signaling PMID: 24928510
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    BIT61 family
  • 数据库链接：

    KEGG: spo:SPCC777.08c

    STRING: 4896.SPCC777.08c.1