Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Schizosaccharomyces pombe Transcription factor tau subunit sfc1 (sfc1)

Recombinant Schizosaccharomyces pombe Transcription factor tau subunit sfc1 (sfc1)

  • 中文名称：
    庞贝裂殖酵母sfc1重组蛋白
  • 货号：
    CSB-YP517645SXV
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    庞贝裂殖酵母sfc1重组蛋白
  • 货号：
    CSB-EP517645SXV
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    庞贝裂殖酵母sfc1重组蛋白
  • 货号：
    CSB-EP517645SXV-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    庞贝裂殖酵母sfc1重组蛋白
  • 货号：
    CSB-BP517645SXV
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    庞贝裂殖酵母sfc1重组蛋白
  • 货号：
    CSB-MP517645SXV
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    sfc1
  • Uniprot No.：
  • 别名：
    sfc1; tfc1; SPAC6F12.11c; Transcription factor tau subunit sfc1; TFIIIC subunit sfc1; Transcription factor C subunit 1
  • 种属：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-456
  • 氨基酸序列
    MNSLKISDNE YALIEHPGFA NNKDAFFQTL GGVQSIQKAC QTSFQNPKQA LLELNLRPKD KYHHPVQARV QSRNDLLVTI KKMDNSVQNV SRIRQVFLFR DMADFQYSTQ NSPFVQKLDS TLRVLDYNAI NKFSIDLTPV QRKHVDMPPP PVFSQTSLPM SYNFLQNPLV GRVRLPNGKT TIVNLKGQCR VWIITTNMGV ESVPTCRHSK LGEPSKTIQE VIEALKPLFE KRPVWTRRAL LNHLDPSYTH YLKFALPYLS YLWTSGPFRD TYTRFGYDPR KDSNAAAYQA LFFKLKLNGK HKGTKTHVFD GKTLFPTNRV YQVCDIVDPT IAPLLKDTQL RSECHRDTGW YRSGRYYKVR DLMREKLFAL IEGEMPSEVA VNMILNAEEV EESDRYSNFD EQDNTDLNDT VRGLNTSATD DRINDLMRNL MKRSQEHEGF EDLEEIDDDY DDIFGD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function. Part of the tauA domain of TFIIIC that binds boxA DNA promoter sites of tRNA and similar genes. Participates in the interconnection of tauA with tauB via its contacts with sfc3 and sfc6. Serves as a scaffold critical for tauA-DNA spatial configuration and tauB-DNA stability. Localizes to chromatin insulator sequence without recruiting RNA polymerase III and plays a role in nuclear organization.
  • 基因功能参考文献：
    1. The N-terminal Sfc1/Sfc7 dimerization module consists of a triple beta-barrel similar to the N-terminal TFIIF Rap30/Rap74 dimerization module. PMID: 23921640
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    KEGG: spo:SPAC6F12.11c

    STRING: 4896.SPAC6F12.11c.1