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  4. Recombinant Sheep Perilipin-5 (Plin5)

Recombinant Sheep Perilipin-5 (Plin5)

  • 货号：
    CSB-YP539613SH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP539613SH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP539613SH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP539613SH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP539613SH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Plin5; Lsdp5; Perilipin-5; Lipid storage droplet protein 5
  • 种属：
    Ovis aries (Sheep)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-456
  • 氨基酸序列
    MSEDEAAQAP GPSLSEQDQQ SAVQRVAALP LIRATCTAVS EAYSAAKDRH PLLGSACRLA EHCVCDLTTR ALDHAQPLLS HLQPQLATVN DLACRGLDKL EEKLPFLQQP SETVVTSAKG VVASSVTGMV GLARQGRRWS VELKRSVSHA MDVVLEKSEE LVDHFLPMTE EELAALAAEA EGPEVGSVEE QRKHQGYFVR LGSLSTRLRH LAYEHSLGKL RQKKHHAQDT LAQLQETLEL IHRMQCGVTP ITPARPGKVH ELWEDWSQRP LENGRRRHSQ AELETLVLSR NLMRELQSTV DALETSVRGL PPSAQEKVAE VRRSVDALQA AFADARRFGD LPAAVLAEGR GSMARAHACV DELLELVVQA MPLPWLVGPF APILVERPEP PPDLEALVDE VIGGPDPRWA HLDWPAQQRA WQAQHGEGTV LSGNIPEEEP EPPSRPKHTL MPELDF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE.
  • 亚细胞定位：
    Lipid droplet. Cytoplasm. Mitochondrion.
  • 蛋白家族：
    Perilipin family
  • 数据库链接：

    KEGG: oas:100135434

    UniGene: Oar.14617