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  4. Recombinant Spindle assembly abnormal protein 5 (sas-5)

Recombinant Spindle assembly abnormal protein 5 (sas-5)

  • 货号：
    CSB-YP632359CXY
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP632359CXY
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP632359CXY-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP632359CXY
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP632359CXY
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    sas-5
  • Uniprot No.：
  • 别名：
    sas-5; F35B12.5; Spindle assembly abnormal protein 5
  • 种属：
    Caenorhabditis elegans
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-404
  • 氨基酸序列
    MNNYDDLPCS IYFKKPTVQE FVDQPRVFED SEVPAFQEVL QLPQERTKPP VPSTQPIVAA VEVAKKKSCL SAPKPRKEPP SHPALRQKTV AFGKTVNVSQ TVEGTSRNSK KVLASTMSAQ NTTTTEEQAA ENWRDAMKTE LQTIRTEIQE ETARRQEELN AQNLVKMQEL MSNFFQKITI PKQQAIEPVE KDKENFHESP RQSRQQKPAS KIASAREVIK RDGVIPPEAL TIIEQRLRSD PMFRQQIDNV LADAECDANR AAYSPPPPMS EVRYGSGVNP ALMRETLTVE RSIRYDNGLA SIDSRQWTNE RRDNRAPDSY RTYEPDQPCH SLYQKGQSIS YYPSEAAGKT TARNNRTGYY VEDSSDHEED VVVNKRGQNY HEQAVPETPA ERERRIREKY ARRK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for centrosome duplication. Essential for daughter-centriole formation. Requires both maternal and partenal expression, suggesting that it regulates centriole duplication during both spermatogenesis and early embryogenesis.
  • 基因功能参考文献：
    1. Disruption of either domain leads to centriole duplication failure in worm embryos, indicating that large SAS-5 assemblies are necessary for function in vivo. PMID: 26023830
    2. SAS-5 has a role in nuclear morphology in Caenorhabditis elegans PMID: 15724817
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to centrioles. Shuttles between centrioles and the cytoplasm throughout the cell cycle. Requires zyg-1 and dephosphorylation by the PP2A complex for centriole localization.
  • 数据库链接：

    KEGG: cel:CELE_F35B12.5

    STRING: 6239.F35B12.5a

    UniGene: Cel.3763