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  4. Recombinant Staphylococcus aureus Transcriptional regulator sarA (sarA)

Recombinant Staphylococcus aureus Transcriptional regulator sarA (sarA)

  • 中文名称：
    金黄色酿脓葡萄球菌sarA重组蛋白
  • 货号：
    CSB-YP640262FLF
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    金黄色酿脓葡萄球菌sarA重组蛋白
  • 货号：
    CSB-EP640262FLF
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    金黄色酿脓葡萄球菌sarA重组蛋白
  • 货号：
    CSB-EP640262FLF-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    金黄色酿脓葡萄球菌sarA重组蛋白
  • 货号：
    CSB-BP640262FLF
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    金黄色酿脓葡萄球菌sarA重组蛋白
  • 货号：
    CSB-MP640262FLF
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    sarA
  • Uniprot No.：
  • 别名：
    sarA; SAOUHSC_00620; Transcriptional regulator SarA; Staphylococcal accessory regulator A
  • 种属：
    Staphylococcus aureus (strain NCTC 8325)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-124
  • 氨基酸序列
    AITKINDCF ELLSMVTYAD KLKSLIKKEF SISFEEFAVL TYISENKEKE YYLKDIINHL NYKQPQVVKA VKILSQEDYF DKKRNEHDER TVLILVNAQQ RKKIESLLSR VNKRITEANN EIEL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Global regulator with both positive and negative effects that controls expression of several virulence factors and biofilm formation process in a cell density-dependent manner. In a strain-dependent manner plays a role in multidrug resistance mechanism. Is required for transcription of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus. Acts as a transcriptional activator of the genes encoding, among others, for fibronectin binding proteins (fnbA and fnbB), hemolysins (hla, hld, hlgB and hlgC), serine proteases (splA, splB, splD and splF) and of the bap gene, which is essential for biofilm development in some strains. Negatively regulates the expression of the genes for protein A (spa), lipase (lip), thermonuclease (nuc), immunodominant staphylococcal antigen B (isaB), staphylococcal serine and cysteine proteases (sspA and sspB), staphostatin B (sspC), metalloprotease aureolysin (aur) and collagen adhesin (cna). Probably activates the development of biofilm by both enhancing the ica operon transcription and suppressing the transcription of either a protein involved in the turnover of PIA/PNAG or a repressor of its synthesis, whose expression would be sigma-B-dependent.
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    SarA family
  • 数据库链接：

    KEGG: sao:SAOUHSC_00620

    STRING: 93061.SAOUHSC_00620