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  4. Recombinant Suid herpesvirus 1 Virion host shutoff protein (VHS)

Recombinant Suid herpesvirus 1 Virion host shutoff protein (VHS)

  • 中文名称：
    Recombinant Suid herpesvirus 1 Virion host shutoff protein(VHS),Yeast
  • 货号：
    CSB-YP327524SRI
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Suid herpesvirus 1 Virion host shutoff protein(VHS),Yeast
  • 货号：
    CSB-EP327524SRI
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Suid herpesvirus 1 Virion host shutoff protein(VHS),Yeast
  • 货号：
    CSB-EP327524SRI-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Suid herpesvirus 1 Virion host shutoff protein(VHS),Yeast
  • 货号：
    CSB-BP327524SRI
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Suid herpesvirus 1 Virion host shutoff protein(VHS),Yeast
  • 货号：
    CSB-MP327524SRI
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    VHS
  • Uniprot No.：
  • 别名：
    VHS; Virion host shutoff protein; Vhs; EC 3.1.27.-
  • 种属：
    Suid herpesvirus 1 (strain Kaplan) (SuHV-1) (Pseudorabies virus (strain Kaplan))
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-365
  • 氨基酸序列
    MGLFGLLKYA HRHRLVRSEA ISTPPGVLTP IAIDLWNVMY TLMEKHYQET TEDNATTTAR CLLRLLRMLH KRTYFPIFVS DRGIFGNGRI ARGAKAIMAA AVRADGDGAA DAPPRPRWST MLHAPRIVHR LCVNLIRHMG YAYVDVSDME ADDVCANLYH TNTVAQVHTT DTDMILTGCD MILDIAPVFP LVLRCRDVLA SLGVDYSEFL AAFVRCHTDL HRAPDVDSVQ QVAESLEGRE VAPEDVKLKY ASRCPDIMRD AGKALALLPA AGDARSPRAE REFIQHVVAM LTPARHGHLS VLRRVPIVQE PSDVNKVFGS LLRHVKNETR AKELAGLFWK HIPPPPNYQA VLMAYWDDCN AHRRK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Minor structural protein that acts as an endoribonuclease during lytic infection. Degrades host mRNAs in the cytoplasm by cutting them at preferred sites, including some in regions of translation initiation.
  • 基因功能参考文献：
    1. Compared to wild type, UL41 null Pseudorabies virus (PRV) shows impaired both replication capability in vitro and lethality in vivo. Further UL41 protein of PRV variant shows significantly weaker virion host shutoff (vhs) activity than that of PRV SC (European-American-like strain), suggesting the deficiency of vhs activity by the PRV variant UL41 protein. PMID: 30071879
    2. The pseudorabies virus (PrV) virion host shutoff (vhs) protein is able to degrade ssRNA and mRNA. However, PrV vhs also targeted rRNA for degradation, which is novel compared to the human simplex virus-1 vhs. PMID: 26704628
  • 亚细胞定位：
    Virion.
  • 蛋白家族：
    Herpesviridae VHS protein family
  • 数据库链接：

    KEGG: vg:2952522