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  4. Recombinant Xenopus laevis Deleted in azoospermia-like-A (dazl-a)

Recombinant Xenopus laevis Deleted in azoospermia-like-A (dazl-a)

  • 中文名称：
    Recombinant Xenopus laevis Deleted in azoospermia-like-A(dazl-a),Yeast
  • 货号：
    CSB-YP528810XBE
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Xenopus laevis Deleted in azoospermia-like-A(dazl-a),Yeast
  • 货号：
    CSB-EP528810XBE
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Xenopus laevis Deleted in azoospermia-like-A(dazl-a),Yeast
  • 货号：
    CSB-EP528810XBE-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Xenopus laevis Deleted in azoospermia-like-A(dazl-a),Yeast
  • 货号：
    CSB-BP528810XBE
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Xenopus laevis Deleted in azoospermia-like-A(dazl-a),Yeast
  • 货号：
    CSB-MP528810XBE
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    dazl-a
  • Uniprot No.：
  • 别名：
    dazl-aDeleted in azoospermia-like-A; DAZ-like protein A; xDazl-A
  • 种属：
    Xenopus laevis (African clawed frog)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-286
  • 氨基酸序列
    MSGKEESSNY AATAEEEAVN QGFVLPEGEI MPNTVFVGGI DITMDEIEIR DFFTRFGNVK EVKIITDRTG VSKGYGFISF SDEVDVQKIV KSQISFHGKK LKLGPAIRKI CTYVQPRPVV LSHPTPFHHA WNNQNADSYI QHSPIVSPIT QYVQACPYPS SPPMAIQQIP VGCQQPGYFQ VSPQWPADQR SYMFPTPAFT FNYHCCDMDP NGGEPIPREY PIDQTVSASG ANPQKRYVEM STQTIVSCLF DPANKFHSFV SQEDYLKDNR VHHLRRRESV IKRVSK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    RNA-binding protein that is required for primordial germ cell (PGC) differentiation and indirectly necessary for the migration of PGCs through the endoderm. May promote meiotic cell division during spermatogenesis. Shows a preference for G- and U-rich RNAs and probably binds the 3'-UTR of target mRNAs. Stimulates the initiation of translation of mRNAs through the recruitment of poly(A)-binding proteins (PABPs).
  • 基因功能参考文献：
    1. The dynamic intracellular localization suggests that Dazl is a multifunctional protein regulating RNA metabolism required for Xenopus germline development PMID: 25963278
    2. Daz- and pumilio-like genes are asymmetrically localized in Pelophylax (Rana) oocytes and are expressed during early spermatogenesis. PMID: 21344644
    3. Dazl has the ability to stimulate translation and function at the level of translation initiation. PMID: 16001084
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    RRM DAZ family
  • 组织特异性：
    Germ-line specific. Oocyte mRNA expression is first restricted to the granulo-fibrillar material (GFM) of the mitochondrial cloud and then to the oocyte germ plasm at the vegetal cortex. Remains an mRNA component of the germ plasm until the neurula stage.
  • 数据库链接：

    KEGG: xla:398041

    UniGene: Xl.311