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  4. Recombinant Xenopus laevis Forkhead box protein A4-A (foxa4-a)

Recombinant Xenopus laevis Forkhead box protein A4-A (foxa4-a)

  • 中文名称：
    有爪蟾蜍foxa4-a重组蛋白
  • 货号：
    CSB-YP339328XBE
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    有爪蟾蜍foxa4-a重组蛋白
  • 货号：
    CSB-EP339328XBE
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    有爪蟾蜍foxa4-a重组蛋白
  • 货号：
    CSB-EP339328XBE-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    有爪蟾蜍foxa4-a重组蛋白
  • 货号：
    CSB-BP339328XBE
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    有爪蟾蜍foxa4-a重组蛋白
  • 货号：
    CSB-MP339328XBE
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    foxa4-a
  • Uniprot No.：
  • 别名：
    foxa4-aForkhead box protein A4-A; FoxA4-A; FoxA4a; Fork head domain-related protein 1; xFD-1; Protein pintallavis
  • 种属：
    Xenopus laevis (African clawed frog)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-399
  • 氨基酸序列
    MLNRVKLEIK DPMDWNTMYQ ENEMYSGIHN MTNVLPSNSF LPNDVSTVTT SMPYMSNGLP GPVTSIQGNI GSLGSMPQGM VGSLAPPPST AAYPLGYCQG ESEFQRDPRT YRRNYSHAKP PYSYISLITM AIQQAPNKMM TLNEIYQWII DLFPYYRQNQ QRWQNSIRHS LSFNDCFVKV PRSPEKPGKG SYWTLHPESG NMFENGCYLR RQKRFKCERS KSGEGEKKVN KPGEETGGNL KENPVGYDDC SSSRSPQAAV NDGGRDSTGS SIHQACGSSP VGLSPTSEQA GTASQLMYPL GLSNDGYLGL VGEDVHLKHD PFSGRHPFSI TQLMSSEQDQ TYANKMEMCP TTDHLVHYSN YSSDYHNMAS KNGLDMQTSS STDNGYYANM YSRPILSSL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional repressor involved in embryonic nervous system development. Plays a role in the induction and patterning of the anterior-posterior neural axis. Involved in the establishment of floor plate differentiation from neural plate cells during gastrulation. Binds the anf1 promoter sequence to restrict expression of anf1 to the anterior of the neural plate, thereby patterning the forebrain. Can bind to the HNF-3-alpha DNA target sequence. Cooperates with t/bra in a dose-dependent manner to specify dorsal mesoderm formation, including notochord. Binds to DNA via the target sequence 5'-[GA]TAAA[TC]A-3', with 5'-GTAAATA-3' being the preferred binding site.
  • 基因功能参考文献：
    1. FoxA4 prevents the respecification of dorsal midline precursors towards contiguous fates, inhibiting prechordal and paraxial mesoderm development in favour of the notochord. PMID: 25343614
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    During stages 8.5 to 10, expressed in the part of the dorsal mesoderm invaginating the dorsal blastopore lip (Spemann organizer), as a direct response to dorsal mesodermal induction. At stage 12 (mid-gastrulation), restricted to the dorsal midline in the
  • 数据库链接：

    KEGG: xla:394304

    UniGene: Xl.441